Female adolescents who experience anxiety will have an increase in prostaglandin synthesis accompanied by decreased levels of estrogen or progesterone, causing uterine muscle contractions, uterine blood flow, uterine ischemia resulting in dysmenorrhea. The prevalence of dysmenorrhoea varies between 15.8% - 89.5%, with the highest prevalence in adolescents, this shows that adolescents are very vulnerable to anxiety which will lead to the incidence of dysmenorrhoea. This study aims to determine the correlation between the level of anxiety during the Covid-19 pandemic and the incidence of primary dysmenorrhoea in adolescents at SMAN 1 Sindang Indramayu in 2020. Non-experimental research with correlational analytic design with cross sectional approach using primary data of 50 female adolescents who were taken by quota sampling technique. Collecting data using an electronic questionnaire which is analyzed by the Spearman rank test. In the univariate analysis, 36% of 50 female adolescents had mild anxiety and 72% had mild primary dysmenorrhoea. Bivariate analysis with the Spearman rank statistical test obtained significance or P value = 0.003 <0.05 and a correlation coefficient value of 0.418 and is positive. There are correlation between the level of anxiety during Covid-19 pandemic and the incidence of primary dysmenorrhoea in female adolescents at SMAN 1 Sindang Indramayu with the strength of the correlation between two variables in the sufficient category and positive, which means that if the variable level of anxiety is high, the primary dysmenorrhoea variable is getting higher.