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DESCRIPTIONA previously healthy 9-year-old girl was admitted to the emergency department of a district hospital due to persistent headache for 3 days. Somnolence, fever and meningismus were noticed. No previous infections or recent immunisations were reported. The child had leucocytosis with elevated C reactive protein. Cerebrospinal fluid (CSF) analysis showed pleocytosis of 96 cells, 73% of lymphocytes, with negative bacteriological, enterovirus and herpes simplex virus screen. Ceftriaxone was started. Owing to persistent fever and headache, a brain CT scan was performed, showing no abnormalities. Focal and generalised seizures started by the ninth day of disease, followed by right-sided Todd hemiparesis. A second lumbar puncture showed increased pleocytosis (316 cells, 66% of lymphocytes). Acyclovir and vancomycin were added and the patient was transferred to our hospital with the diagnostic hypothesis of meningoencephalitis. On admission, she presented a normal level of consciousness, and the physical examination showed flaccid paraparesis, pain and vibratory hypoesthesia below T2 and bilateral cervical adenopathy. Ciprofloxacin was added. Brain MRI revealed leptomeningeal enhancement with no basal ganglia or thalami involvement. Spinal cord MRI showed a longitudinally extensive transverse myelitis (figures 1 and 2). Neoplastic and autoimmune causes were ruled out, including negative neuromyelitis optica IgG (NMO-IgG). The extensive microbiological screening revealed positivity for Epstein-Barr virus (EBV) DNA in blood (6.5×10 3 copies of EBV DNA/mL) and in CSF (900 copies of EBV DNA/ mL), with positive early EBV IgG and borderline EBV IgM. Treatment included a 5-day course of immunoglobulin and 28-day course of endovenous ganciclovir followed by oral valganciclovir. The patient gradually improved, regaining ability to walk, though maintaining a neurogenic bladder and left foot drop. Figure 1 Spinal cord MRI, sagittal T2-weighted images showing a hyperintense lesion on T2-weighted sequence, centrally located, occupying more than two-thirds of the cross-sectional area and leading to spinal cord expansion, extending from D2 to D10. There was no significant enhancement with gadolinium. Figure 2 Spinal cord MRI, axial T2-weighted images showing a hyperintense lesion on T2-weighted sequence, centrally located, occupying more than two-thirds of the cross-sectional area and leading to spinal cord expansion, extending from D2 to D10. There was no significant enhancement with gadolinium.

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Abstract:In this paper we present the annotation of a corpus with named entities that are classified into semantic types and disambiguated by linking them to their corresponding entry in the Portuguese DBpedia. This corpus, QTLeap Corpus, is a multilingual collection of question and answer pairs from a chat-based helpdesk service for Information and Communication Technologies. The resulting annotated corpus is a gold-standard named entity annotated lexical resource that is useful in supporting the training and evaluation of named entity annotation and disambiguation tools for Portuguese.