ABSTRAK Resistensi antimikroba merupakan kejadian yang rentan terjadi pada masa ini yang salah satunya disebabkan oleh penggunaan antimikroba yang tidak bijak. Untuk memerbaiki data resistensi terhadap mikroba diperluka suatu upaya untuk mengendalikan terjadinya resistensi antimikroba. Kegiatan yang dapat dilakukan salah satunya adalah menggunakan antimikroba dengan bijak yang dapat dilakukan dengan melakukan evaluasi penggunaan antimikroba kuantitatif dan kualitatif secara berkala. Penelitian dilakukan di ruang rawat inap dewasa salah satu rumah sakit swasta di Kabupaten Karawang dengan kegiatan kajian analisis tingkat pemakaian antimikroba dengan metoda sesuai dianjurkan WHO ATC/DDD menggunakan aplikasi AMC tool. Penelitian dilakukan dengan metoda deskripsi analitis dengan purposive sampling pada 165 pasien dengan 141 () menggunakan terapi dengan antimikroba dan 24() menggunakan terapi non antimikroba. Hasil penelitian menunjukkan nilai antimicroba comsumtion index (ACI) sebesar 121, 57DDD/100 hari rawat dengan pemakaian jenis antimikroba tertinggi adalah golongan sefalosporin ceftriaxone 67,851 DDD/hari rawat, etambutol 16,23 DDD/hari rawat (13,36%) dan sefuroksim 11,89DDD/hari rawat (9,79%) Kata Kunci : resistensi antimikroba, ATC/DDD, Antibiotika, DDD/100 hari rawat, Sefalosporin ABSTRACT Antimicrobial resistance is an incident that occurred during this vulnerable, one of which was caused by Unwised use of an antimicrobial. To repair a resistance to microbial data need an effort to control the occurrence of antimicrobial resistance. Programs that can be done by using antimicrobial wisely by doing an evaluation of antimicrobial use quantitative and qualitative periodically. Research conducted in adult inpatient one private hospital in Karawang. Study of antimicrobial usage level analysis method in accordance with recommended WHO ATC/DDD using AMC application tool. Methode of research analytical description with purposive sampling on 165 patients with 141 patients using therapy with antimicrobial and 24 patient use a non therapeutic antimicrobials. The results showed the value antimicroba comsumtion index (ACI) of 121, 57DDD/bed days and ceftriaxone 67,851 DDD/bed days (55,86%), ethambutol 16,23 DDD/bed days ( 13,36%) and cefuroxime 11,89 DDD/bed days (9,79%) as the highest used antimicroba Keywords : antimicrobial resistance, ATC/DDD method, antibiotic, DDD/100 bed days, cephalosporins
Objectives: The purpose of the research was to describe drug-related issues and assess the effect of communication between pharmacists and physicians on decreased prescription drug-related problems in pediatric antibiotics. Methods:Intervention was carried out in the form of pharmacist discussing information-related issues about drugs with physicians prescribing antibiotics to pediatric patients. The research sample included 338 prescription sheets on pediatric outpatient use of antibiotics, and a prospective design was used. Analysis of the data was carried out in the form of a frequency distribution and bivariate analysis Wilcoxon test. Results:The results showed that drug-related problems were recorded on 62.22% of the 338 prescription sheets. The biggest problems that occurred had to do with the effectiveness of therapy (P1; 79.3%) and cost issues (P1; 20.7%). In terms of P1, drug-related problems involved excessive frequency of drug administration (80.1%), inappropriate drug dose selection (17.2%), drug interactions (9.6%), inadequate drug selection (12.2%), a subtherapeutic dose (4.1%), and excessive drug dose (0.5%). For P1, therapy cost problems were a lack of indication for the drug (84.1%) and improper drug selection (15.9%). Conclusions:The influence of pharmacist-physician communication concerning the reduction of drug-related problems for pediatric outpatient prescriptions was statistically significant (p<0.05). Ultimately, communication between pharmacists and physicians can reduce drug-related problems by 22.9%.
Stunting adalah suatu proses yang berdampak pada perkembangan anak mulai dari tahap dini, yakni saat konsepsi hingga tahun ke-3 atau ke-4 kehidupan anak, dimana keadaan gizi ibu dan anak merupakan faktor penting dari pertumbuhan anak. Tujuan penelitian untuk melihat hubungan sikap dan pengetahuan terhadap tingkat kepatuhan penggunaan Fe pada ibu hamil di Puskesmas Klari. Penelitian ini dilakukan dengan jenis penelitian analitik prospektif dengan pendekatan korelasi. Berdasarkan hasil penelitian di Puskesmas Klari yang telah diuji dengan menggunakan metode Chi-Square, terdapat hubungan yang signifikan pada Puskesmas Klari dengan nilai p-value 0,001 (pv<0,05) artinya, tingkat sikap memiliki hubungan dengan kepatuhan penggunaan Fe pada ibu hamil dan tingkat pengetahuan memiliki hubungan dengan kepatuhan penggunaan Fe pada ibu hamil.
Stunting merupakan masalah gizi kronis yang bersifat antargenerasi dan disebabkan oleh multifaktorial. Hasil studi membuktikan bahwa pengaruh faktor keturunan hanya berkontribusi sebesar 15%, sementara unsur terbesar adalah terkait masalah asupan gizi, hormon pertumbuhan dan terjadinya penyakit infeksi berulang. Salah satu asupan gizi yang perlu diperhatikan ibu hamil adalah zat besi (Fe). Tujuan penelitian untuk melihat hubungan sikap dan pengetahuan terhadap tingkat kepatuhan penggunaan Fe pada ibu hamil di Puskesmas Tirtamulya. Penelitian ini dilakukan dengan jenis penelitian analitik prospektif dengan pendekatan korelasi. Berdasarkan hasil penelitian di Puskesmas Tirtamulya yang telah diuji dengan menggunakan metode Chi-Square, terdapat hubungan yang signifikan pada Puskesmas Tirtamulya dengan nilai p-value 0,001 (pv < 0,05) artinya, tingkat sikap memiliki hubungan dengan kepatuhan penggunaan Fe pada ibu hamil dan tingkat pengetahuan memiliki hubungan dengan kepatuhan penggunaan Fe pada ibu hamil.
Aims: This study aims to determine the level of drug adherence in patients with pulmonary tuberculosis at the Cilamaya Kulon Primary Health Center area, Karawang Regency, West Java, Indonesia. Study Design: The measurement of adherence level was carried out using the MMAS (Morisky Medication Adherence Scale) instrument. Place and Duration of Study: This study was conducted at Cilamaya Kulon Primary Health Center area, specifically in Bayur Lor and Pasirukem Primary Health Centers, Karawang Regency, West Java, Indonesia, from July to September 2021. Methodology: A cross-sectional design with a purposive sampling data collection method was used. Furthermore, the subjects were pulmonary TB patients from the Bayur Lor and Pasirukem Primary Health Centers, Karawang Regency. The instrument used was the MMAS questionnaire sheet, and data analysis was performed using SPSS (version 22.0) and continued with statistical tests using the chi-square test. Results: The results showed there was no significant relationship (p>0.05) between age, gender, educational status, employment status, income level, smoking status, duration of treatment, drugs side effects, medication supervision, and patient motivation for drugs adherence in the Cilamaya Kulon Primary Health Center area. Furthermore, the level of medication adherence of pulmonary TB patients at this Primary Health Center area was high with a value of 84.13%. Conclusion: Adherence to medication in pulmonary TB patients was not influenced by age, gender, educational status, employment status, income level, smoking status, duration of treatment, drug side effects, medication supervision, and patient motivation. Therefore, the adherence level is included in the high category.
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