Introduction: This study assessed the role of gut bacteria in the development of type 2 Diabetes Mellitus. Methodology: Using bacteria cultural method, microbial species were isolated from feacal materials, identified and quantitated through application of genomic spectrophotometric systems with a quantitation of some marker biochemical parameters for Diabetes. Result: We observed a concentration of firmicutes, bacteriodetes, protecbacteria and bifidobacterium with Escherichia coli population predominating. Biochemical parameters reveal a 3-fold raised value for some bromakers in type 2 diabetes. At a confidence interval of 95% paired sample test results gave significant differences for all tested pairs. Conclusion: Result suggests that microbiomes have the potential to alter the gut environment and cause changes that promote the development of type 2 diabetes.
Cases of neonatal jaundice due to Hyperbilirubinemia abound with some resulting in mortality especially arising from complications in Ceaserean Section. We studied biochemical patterns of some enzymes, hormones and other parameters in 1 - 4 days old neonates. Using spectrophotometnc and radioimmunoassay techniques we measured biochemical liver function parameters bilirubin, transaminases and gammaglutamyltransferase. Hormonal evaluation included cortisol, glucagon and adrenocortical hormone. Using SPSS version 23, paired sample test at 95% confidence intervals of difference shows 2 tail significance for bilirubin, transaminase; giucagon, cortisol and ACTH. Paired sample correlation also showed strong negative pattern with days. We conclude that the interplay of nervous system and self-regulating influence of stress hormones coupled with an immature liver triggers the formation of excess bilirubin.
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