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Berger el a1.l have shown that carisoprodol does not show any detectable analgesic action when tested by the methods of Woolfe and MacDonald2 but that, with the silver-nitrate method of LaBelle and T i~l o w ,~ such action can be detected. The rat treated with silver nitrate recovers the mobility of the joint after treatment with carisoprodol orally even a t a dose level incapable of exercising a hypotonic effect. Using two methods, we have evaluated the central analgesic action and the myorelaxant effect of carisoprodol.