The Total Synthesis of Lysergic Acid 3087 in the ultracentrifuge,8'41 as are polysaccharides generally.With respect to immunological homogeneity it has been established by several investigators that proteins which are non-homogeneous in the ultracentrifuge,42 electrophoretically4 3 and in amino acid composition31 may be immunochemically uniform.The relationship of amino acid composition to specificity among the blood group substances is not clear from the data presented. Work on the inhibition by oligosaccharides of the precipitation of blood group substances with specific antibody suggests that the carbohydrate presents binding sites for the immunological reaction.44 In view of the general similarity of amino acid composition, it is (41) R. A.

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