BACKGROUND Eclampsia is a preventable disease be prevented by making women aware of the avoidable risk factors during their antenatal visits and thereby decreasing the incidence of eclampsia and associated morbidity, mortality and perinatal outcome. Aim-To study the association of sociodemography as a risk factor for eclampsia. Objective-To compare the various parameters of sociodemographic risk factors (namely age, residence, education and socioeconomic status) between the eclamptic and the patients admitted for delivery with no complications. on 282 admitted women. This is a tertiary care hospital and its maternity service is a referral in the care of high risk pregnant women throughout the district. All women selected for the study were divided into two groups, cases and controls. Cases were the patients admitted to labour room with BP >140/90 mmHg, Urine Protein > + 1, with convulsions. Controls were the patients admitted to labour room with BP < 140/90 mmHg, Urine Protein negative, without convulsions. Their age, education, residence and socioeconomic status were compared and analysed. The X 2 test was used to determine levels of statistical significance wherever appropriate. RESULTS Majority of the cases taken into the study were from less than 20 years of age group and 21-30 years of age i.e., 44.68% and 51.77% respectively. High proportion of eclampsias 68.08% belong to rural area, only 31.92% belong to urban area. Majority of eclampsia (89.36%) cases were associated with high rate of illiteracy (89.36%) as compared to controls (47.51%), belonging to rural area (68.08%) and low socioeconomic conditions. Maximum no. of eclamptic women were from low socioeconomic class i.e., 70.92% from class V, 26.24% from class IV, 1.41% from class III and II each and no women from class I according to Modified B G Prasad Socioeconomic Classification. In our study statistically significant association was observed between eclampsia and risk factors. CONCLUSION Eclampsia is a preventable disease by making the patient aware of the risk factors which can be avoided and thereby decreasing the incidence of eclampsia and associated morbidity and mortality.

The aim of this study was to investigate whether an 8-week treadmill training attenuates exercise-induced oxidative stress in rat liver. Male rats were divided into untrained and trained groups. Endurance training consisted of treadmill running at a speed of 2.1 km/h, 1.5 h/day, 5 days a week for 8 weeks. To see the effects of endurance training on acute exhaustive exercise induced oxidative stress, untrained and trained rats were further devided into two groups: animals killed at rest and those killed after acute exhaustive exercise, in which the rats run at 2.1 km/h (10% uphill) until exhaustion. Acute exhaustive exercise increased malondialdehyde level in untrained but not in trained rats. It decreased the activity of glutathione peroxidase and total (enzymatic plus non-enzymatic) superoxide scavenger activity in untrained rats and catalase activity in trained rats. However, it did not affect glutathione S-transferase, glutathione reductase, superoxide dismutase and non-enzymatic superoxide radical scavenger activities in both trained and untrained rats. On the other hand, endurance training decreased glutathione peroxidase and glutathione S-transferase activities. The results suggested that endurance training attenuated exercise-induced oxidative stress in liver, probably by preventing the decreases in glutathione peroxidase and total superoxide scavenger activities during exercise.

Introduction and Objective TAP block has gained popularity to provide postoperative analgesia after abdominal surgery but its advantage over epidural analgesia is disputed. For lower abdominal surgeries, epidural analgesia has been the gold standard and time-tested technique for providing postoperative analgesia, but contraindications for the same would warrant need for other equally good analgesic techniques. The objective of this study is to compare the analgesic efficacy of both the techniques. Materials and Methods Eighty patients in the ASA I-II risk group, undergone an elective C-section, were randomly assigned to the study. In the TAP group, before the C-section, a single-dose spinal anaesthesia was performed by administering 3 ml of 0.5% hyperbaric bupivacaine to the patients when they were in the sitting position. After the C-section, an ultrasound-guided bilateral TAP block was performed in these patients in the recovery room for postoperative analgesia. In the single-dose EPI group, the patients received 16 cc of isobaric bupivacaine, 3 mg of morphine, and 50 mcg of fentanyl, making a total volume of 20 cc and being administered to the epidural space. Results A higher level of patient satisfaction was observed in the EPI group (p=0.003). The amount (mg) of total analgesics received by the patients in the first 24 hours of the postoperative period was statistically significantly higher (p=0.021) in the TAP group compared to the EPI group. The visual analogue scale (VAS) scores of the EPI group were significantly lower compared to that of the TAP group (p < 0.001). Conclusion The epidural anaesthesia is still the golden standard to achieve a postcaesarean analgesia. Epidural anaesthesia is a considerably effective method in controlling the postoperative pain. We are of the opinion that epidural anaesthesia should be preferred in the first place to achieve a successful postcaesarean analgesia as it provides more effective pain control.

We believe that we have introduced three novel follow-up parameters, such as: IMA, MPO, EFTT to literature for the follow-up of CKD. As the levels of IMA MPO and EFTT increase, the severity of CKD increases (Tab. 4, Fig. 1, Ref. 25).

The present study suggests that left-handedness appears to be a predictor factor for RAS.