BackgroundHealthcare workers are at increased risk of infection due to occupational exposure to SARS-CoV-2-infected patients. The objective of this study was to determine the seroprevalence of SARS-CoV-2 in healthcare workers in Colombia.MethodsThis study is a cross-sectional study focused on estimating the seroprevalence of SARS-CoV-2 antibodies in healthcare workers from 65 hospitals in 10 cities in Colombia during the second semester of 2020. The seroprevalence was determined using an automated immunoassay (Abbott SARS-CoV-2 CLIA IgG). The study included a survey to establish the sociodemographic variables and the risk of infection. A multivariate model was used to evaluate the association between the results of seroprevalence and risk factors.ResultsThe global seroprevalence of antibodies against SARS-CoV-2 was 35% (95% Bayesian CI 33% to 37%). All the personnel reported the use of protective equipment. General services personnel and nurses presented the highest ratios of seroprevalence among the healthcare workers. Low socioeconomic strata have shown a strong association with seropositivity.ConclusionThis study estimates the prevalence of SARS-CoV-2 infection among healthcare workers. Even though all the personnel reported the use of protective equipment, the seroprevalence in the general services personnel and nurses was high. Also, a significant difference by cities was observed.
Objective: To determine the mortality and survival of COVID-19 cases in Colombia between March and July 2020. Materials and methods:A retrospective cohort study in the Colombian population between March 6 to July 8, 2020, with the data reported to the National Institute of Health. Survival analysis was performed considering the real-time PCR results, died or recovered, the onset of symptoms until the date of death, or the final time of the cohort. The actuarial variation and Long-Rank test were applied for survival. Risk factors were determined by Cox regression. Results: The overall survival rate was 100%, 98%, 97%, and 95% for day 1, 10, 20 and 30, respectively. Differences were found in survival in age, sex, region, and hospitalization time spending (p <0.01), the 30-day survival rate was 96% and 95% for females and males, respectively. The region with the highest survival was Antioquia with 99% and the lower Barranquilla with 93%. The age group with the lowest survival was ≥80 years of age with 60%, and being hospitalized represented a survival rate of 68%. Conclusions: This study is one of the first to estimate survival in the Colombian population diagnosed with COVID-19.
Background. Onychoscopy is a technique that uses a dermatoscope for the evaluation of specific features of different skin conditions that are not visible to the naked eye. There are few studies establishing parameters for the diagnosis of onychomycosis based on onychoscopy. Determining the sensitivity and specificity of a potentially new diagnostic test for onychomycosis requires an evaluation study of this new diagnostic test, as there are limited studies reporting onychoscopy results. Aim. To determine the sensitivity, specificity, positive predictive value and negative predictive value of onychoscopy findings in a Colombian population with onychomycosis. Methods. We assessed outpatients with a diagnosis of toenail onychomycosis confirmed by potassium hydroxide preparation or fungal culture. Onychoscopy was performed using a dermatoscope, and digital images collected using a smartphone. Results. The onychoscopy findings were: longitudinal striae, distal spiked pattern, distal irregular termination, linear edge and ruins aspect, while some patients were confirmed as having traumatic onycholysis. A statistically significant association was found between the clinical symptoms of onychomycosis and both the clinical feature of dyschromia and the onychoscopy feature of longitudinal striae. Conclusion. We suggest that this technique is an alternative method that should be used in patients with onychopathies because it has the potential to differentiate onychomycosis from traumatic onycholysis and another nail involvement.
Introducción. El parto pretérmino es aquel que ocurre antes de la semana 37 de gestación. Este tipo de parto se asocia a múltiples factores de riesgo, algunos de los cuales pueden ser prevenidos. En Colombia son escasos los estudios sobre los factores de riesgo asociados al parto pretérmino, de ahí la importancia de su análisis.Objetivo. Identificar los factores de riesgo para parto pretérmino en un grupo de gestantes de Bogotá D.C., Colombia.Materiales y métodos. Estudio de cohorte retrospectivo. La muestra estuvo compuesta por 452 pacientes que habían participado en un estudio primario y que ya habían dado a luz.Resultados. La prevalencia de parto pretérmino fue de 10.4% (IC95%: 7.60-13.20) y los factores de riesgo asociados fueron los siguientes: ser diagnosticada con preeclampsia severa, con un riesgo relativo (RR) de 7.4 (IC95%: 4.59-11.95); tener preeclampsia (severa y no severa), con un RR=5.1 (IC95%: 3.0-8.51), y ocurrencia de restricción del crecimiento intrauterino (RCIU), con un RR=4.4 (IC95%: 2.44-7.98).Conclusiones. De acuerdo con los hallazgos reportados en el presente estudio, es necesario planear e implementar estrategias y políticas públicas en Bogotá D.C. que promuevan mejores prácticas de atención prenatal que, a su vez, permitan la detección temprana de condiciones como la preeclampsia y la RCIU, lo que hará posible reducir la incidencia de partos pretérmino en la ciudad y utilizar la experiencia y resultados obtenidos en el resto del país.
Objetivo. Determinar el estado nutricional de los niños y adolescentes escolares de 17 escuelas del área rural del municipio de La Mesa, Cundinamarca, en 2012.<br />Metodología. Se llevó a cabo un estudio observacional, descriptivo y transversal, en el cual se tomaron medidas antropométricas de peso y talla a 411 niños y adolescentes de 17 escuelas rurales del municipio de La Mesa, en el 2012. Se utilizaron los patrones de crecimiento de la Organización Mundial de la Salud para los niños y adolescentes de 0 a 18 años, adoptados por Colombia en la Resolución 2121 del 2010. Los indicadores utilizados fueron talla para la edad e índice de masa corporal. Se usaron los criterios de clasificación de acuerdo con los puntos de corte establecidos para el país en términos de desviación estándar<br />Resultados. La edad promedio fue de 8,4±2,2 años. Se encontró que la prevalencia de riesgo de talla baja para los escolares menores de 10 años fue de 29,2 %, y en los mayores de esta edad, de 31,4 %. El 59,1 % de los niños y adolescentes del estudio tenía una talla adecuada para la edad y el 10,7 % presentaba talla baja para la edad. En relación con el exceso de peso, el 11,4 % tuvo sobrepeso y el 1,9 % presentó obesidad.<br />Conclusión. Se observó que el 25,2 % de la población escolar del área rural de La Mesa tenía algún compromiso nutricional en cuanto a baja talla para la edad, delgadez, sobrepeso y obesidad. Estos datos ratifican los resultados encontrados en la ENSIN 2010 y expresan problemas por deficiencia de talla para la edad, déficit o exceso de peso para la talla
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