The Artocarpus heterophyllus (Jackfruit) is a species of tree of the mulberry family Moraceae. The plants of Artocarpus species have been used by traditional folk medicine in Indonesia. can be useful as anti-bacterial, antidiabetic, anti-inflammatory, antioxidant and anti-helmintics. The present study was aimed to evaluate antidiabetic and antioxidant activity of aqueous extract of Jackfruit. The antidiabetic activity were determined by inhibition of haemoglobin glycation method. Phytochemical constituent like ascorbic acid, -carotene and lycopene also determined. Antioxidant activity was measured by hydroxl radical and hydrogen peroxide scavenging activity, and chellating effect of ferrous iron. From the result of this study we can see the increasing of haemoglobin glycation concentration is followed by the increasing of jackfruit extracts concentration. From this study also we found the IC 50 of jackfruit exctracts is 56,43 %. The result of this study also showed that the extract of jackfruit has a phytochemical constituent with ascorbic acid is the highest, and followed by -carotene and lycopene. Jackfruit also has antioxidant activity. The highest antioxidant activity is scavenging hydroxyl radical activity and followed by scavenging hydrogen peroxide and chellating of ferrous iron. The result of this study suggest that the jackfruit extract potential as an diabetic agent.
In the present study antioxidant and antioxidant activity of some tropical fruits was evaluated. Antioxidants are compounds or molecules that can scavenging and prevent free radicals and reactive oxygen species that can caused a cell damage. Fruit was known as a source of antioxidant. South Kalimantan Indonesia, has a variety of fruit such as mentega, nangka, timun suri and kuranji. Study for evaluating the antioxidant levels and activity of those fruit were never been investigated. Thus, our study aim to measure the antioxidant levels and antioxidant activtity of those selected fruits. Ascorbic acid, lycopene, b-carotene levels and antioxidant activity of four selected tropical fruits was evaluated using spectrophotometer. The result of this studied suggest that the four selected tropical fruits is potential antioxidant because it contained ascorbic acid, b-carotene, lycopene and had effect of scavenging radical hydroxyl, hydrogen peroxide and chellating ferrous iron.
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