The Artocarpus heterophyllus (Jackfruit) is a species of tree of the mulberry family Moraceae. The plants of Artocarpus species have been used by traditional folk medicine in Indonesia. can be useful as anti-bacterial, antidiabetic, anti-inflammatory, antioxidant and anti-helmintics. The present study was aimed to evaluate antidiabetic and antioxidant activity of aqueous extract of Jackfruit. The antidiabetic activity were determined by inhibition of haemoglobin glycation method. Phytochemical constituent like ascorbic acid, -carotene and lycopene also determined. Antioxidant activity was measured by hydroxl radical and hydrogen peroxide scavenging activity, and chellating effect of ferrous iron. From the result of this study we can see the increasing of haemoglobin glycation concentration is followed by the increasing of jackfruit extracts concentration. From this study also we found the IC 50 of jackfruit exctracts is 56,43 %. The result of this study also showed that the extract of jackfruit has a phytochemical constituent with ascorbic acid is the highest, and followed by -carotene and lycopene. Jackfruit also has antioxidant activity. The highest antioxidant activity is scavenging hydroxyl radical activity and followed by scavenging hydrogen peroxide and chellating of ferrous iron. The result of this study suggest that the jackfruit extract potential as an diabetic agent. 

The development of resistance to chemical insecticides among mosquito species has been considered as a setback in vector control. Therefore, researchers have diverted their attention towards natural products of plant origin with insecticidal properties for control of insects pests and vectors. Papaya (Carica papaya), an herbaceous fruit crop belonging to the family Caricaceae, has garnered popularity among researchers due to its nutritional and pharmaceutical value. Our study aimed to determined the larvicidal effect of aqueus extracts of seed and peel of Carica papaya. The results shows that the seed and peel extracts has a larvicidal activity against Aedes aegypti. The seed extracts has a higher larvicidal activity than peel extracts. This migh be de due the effect of pyhtochemical constituent in extract suc as flavonoid, alkaloid and tannin. From this study indicate that the aqueuous extracts of seed and peel of Carica papaya showed potential larvicidal activity for Aedes aegypti. Further studies might be needed for the used of this extracts for eco-friendly vector control programs especially for Aedes aegypti.

Objective: The present study was undertaken to investigate the anti-metalotoxic activity of the leaves extract of Stenochlaena palustris (kelakai; S. palsutris) on cadmium (Cd)-induced liver tissue damage.Methods: Liver tissue damage was induced by the administration of cadmium sulfate (CdSO4) at a dose 3 mg/l. Anti-metalotoxic effect of the extracts was determined by assessing the concentration of malondialdehyde (MDA), carbonyl compound (CC), conjugated dienes (CD), and advanced oxidation protein products (AOPPs) induced by Cd with and without the presence of the extract.Results: The results of this present studies showed that treatment with CdSO4 significantly increase the levels of MDA, CC, CD, and AOPPs. The leaves extract of S. palustris significantly decrease the levels of all measured parameter in liver tissue.Conclusion: The present study demonstrated that Cd could induced the liver tissue damage, and the extract of S. palsutris showed the anti-metalotoxic activity to reduce the damage.

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Galam (Melaleuca cajuputi subsp. Cumingiana (Turcz.) Barlow) is a peat swamp forest plant. This plant is used to treat respiratory diseases, colitis, sore throat, itchy skin, diarrhea, and dizziness. This study aimed to analyze the antibacterial and antifungal activity of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flowers and fruit against Escherichia coli and Candida albicans bacteria. This research is a pretest-posttest research with control group design and consists of 3 stages of research. The first stage is the phytochemical screening test, the second stage determines the minimum inhibitory concentration (MIC) and the third determines the minimum bactericidal concentration (MBC). The results showed that the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flowers and fruit contained terpenoids, flavonoids, phenols, saponins, quinones, steroids, tannins, while alkaloid compounds only found in the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow fruit. The MIC and MBC values ​​of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flower methanol extract against E. coli were 1.67 and 2.083 mg/mL, respectively, while the MIC and MBC values ​​of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow flower against C. albicans were 3.125 and 25 mg/mL. The MIC and MBC values ​​of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow fruit against E. coli have same value  were 3.334 mg/mL, while the MIC and MBC values ​​of the methanol extract of M. cajuputi subsp. Cumingiana (Turcz.) Barlow fruit against C. albicans were 3.125 and 12.5 mg/mL, respectively. Keywords: Galam  antibacterial, antifungal, Escherichia coli, Candida albicans