The development of resistance to chemical insecticides among mosquito species has been considered as a setback in vector control. Therefore, researchers have diverted their attention towards natural products of plant origin with insecticidal properties for control of insects pests and vectors. Papaya (Carica papaya), an herbaceous fruit crop belonging to the family Caricaceae, has garnered popularity among researchers due to its nutritional and pharmaceutical value. Our study aimed to determined the larvicidal effect of aqueus extracts of seed and peel of Carica papaya. The results shows that the seed and peel extracts has a larvicidal activity against Aedes aegypti. The seed extracts has a higher larvicidal activity than peel extracts. This migh be de due the effect of pyhtochemical constituent in extract suc as flavonoid, alkaloid and tannin. From this study indicate that the aqueuous extracts of seed and peel of Carica papaya showed potential larvicidal activity for Aedes aegypti. Further studies might be needed for the used of this extracts for eco-friendly vector control programs especially for Aedes aegypti.

Haruan is Kalimantan’s indigenous fish which has the potency to accelerate wound healing. Haruan extract has substantial properties such as albumin, Zn, Cu, and Fe to accelerate wound healing. The purpose of this study is to assess the effect of haruan extract on wistar rat’s buccal mucosa wound healing on day 3, 5, and 7 histopathologically. This study was experimental with post-test with control group design. Samples were consisted of 4 treatment groups, 25%, 50%, 100% haruan extract treatment groups and negative control treated with aquadest for 7 days. Mean fibroblast cells count reached its peak on day 7. Mean fibroblast cells count in each group was 26.995; 40.500; 49.165; 24.495 respectively. Two way ANOVA and Post Hoc Least Significant Difference tests indicated there was a significant difference (p<0.05) between haruan extract treatment group and negative control. In conclusion, haruan extract treatment significantly increase fibroblast cells count in wound healing process.

Worm infection is an infectious disease caused by one or more intestinal parasitic worms from the class of intestinal nematodes. Worm infection can disruption of nutrients such as deficiency calories, protein, and blood loss. The aim of research is to know the effect of worm infection on nutritional status in SDN 2 Barabai Darat's children South Kalimantan 2015. This research is an observational analytic with cross sectional approach. The total samples is 85 children from class 3 and 4, obtained by purposive sampling fit the inclusion criteria. Data collected by stool examination and measurement of nutritional status, the data were analyzed by Fischer's Exact test. The results showed were 5,9% children with worm infections. Statistical analysis showed that there was not any effect of worm infection  on nutritional status based on BB/U (p = 1,000), based TB/U (p = 0,154), and based on BMI/U (p = 1,000). Conclusion from this research is not any effect of worm infection on nutritional status in children at SDN 2 Barabai Darat (p> 0,05). Keywords: worm infection, nutritional status, SDN 2 Barabai Darat Abstrak: Infeksi kecacingan adalah suatu penyakit infeksi yang disebabkan oleh satu atau lebih cacing parasit usus dari golongan nematoda usus. Infeksi kecacingan dapat menimbulkan gangguan zat gizi berupa kekurangan kalori, protein, dan kehilangan darah. Tujuan penelitian adalah untuk mengetahui pengaruh infeksi kecacingan terhadap status gizi pada anak di SDN 2 Barabai Darat Kalimantan Selatan tahun 2015. Jenis penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan cross sectional. Jumlah sampel sebanyak 85 anak dari kelas 3 dan 4, didapat secara purposive sampling  sesuai kriteria inklusi. Pengumpulan data dilakukan dengan pemeriksaan feses dan pengukuran status gizi, sedangkan analisis data dilakukan dengan menggunakan uji Fischer's Exact. Hasil penelitian menunjukkan terdapat 5,9% anak yang positif terinfeksi cacing. Analisis statistik menunjukkan bahwa tidak terdapat pengaruh infeksi kecacingan terhadap status gizi berdasarkan BB/U (p=1,000), berdasarkan TB/U (p=0,154), dan berdasarkan IMT/U (p=1,000). Kesimpulan penelitian ini adalah tidak terdapat pengaruh infeksi kecacingan terhadap status gizi pada anak di SDN 2 Barabai Darat (p>0,05). Kata-kata kunci: kecacingan, status gizi, SDN 2 Barabai Darat

Diarrhea is a contagious disease which still become public health main issue in the world includes Indonesia. South Borneo is in the twentieth province with most frequent diarrhea incident. Kelayan Timur is the second most frequent diarrhea incident public health center in Banjarmasin. One of the risk factors for diarrhea is milk bottle hygiene. This research aimed to understand the correlation between milk bottle hygiene and diarrhea incident in Kelayan Timur Public Health Center. This was analytic observational research with case control study. The data analyzed using a chi square test and prevalence odds ratio. There were 66 samples with 33 samples of case group which showed 21 samples (63,63%) of poor milk bottle hygiene and 12 samples (36,36%) of good milk bottle hygiene meanwhile in control group, there were 11 samples (33,33%) of poor milk bottle hygiene and 22 sample (66,66%) of good milk bottle hygiene. Analysis result shows p value=0,014 and OR=3,5 which means there is significant relation of milk bottle hygiene and diarrhea incident in Kelayan Timur Public Health Center. Infants with poor hygiene milk bottle have 3,5 times higher risk to suffer from diarrhea than infants with good hygiene. Keywords: milk bottle hygiene, diarrhea, Kelayan Timur Public Health Center Abstrak: Diare adalah penyakit infeksi menular yang masih menjadi masalah utama kesehatan masyarakat di seluruh dunia termasuk Indonesia. Kalimantan Selatan menduduki urutan kedua puluh dari semua provinsi yang tercatat sebagai daerah penyumbang diare terbanyak. Kelayan Timur adalah puskesmas dengan kejadian diare terbanyak kedua di Banjarmasin. Salah satu dari faktor risiko diare adalah higienitas botol susu. Penelitian ini bertujuan untuk mengetahui hubungan higienitas botol susu dengan kejadian diare di wilayah Puskesmas Kelayan Timur. Penelitian bersifat observasional analitik dengan pendekatan case control. Analisis data menggunakan uji Chi-square dan prevalence odds ratio.Sampel yang diambil sebanyak 66 sampel, dimana 33 sampel yang diambil sebagai kelompok kasus menunjukkan 21 sampel (63,63%) dengan higienitas botol susu yang buruk dan 12 sampel (36,36%) dengan higienitas botol susu yang baik, sedangkan pada kelompok kontrol terdapat 11 sampel (33,33%)  dengan higienitas botol susu yang buruk dan 22 sampel (66,66%)  dengan higienitas botol susu yang baik. Hasil analisis mendapatkan nilai p=0,014 dan OR=3,5 sehingga dapat disimpulkan bahwa terdapat hubungan bermakna antara higienitas botol susu dengan kejadian diare di wilayah Puskesmas Kelayan Timur. Balita dengan higienitas botol susu yang buruk berisiko 3,5 kali lebih besar untuk menderita diare dibanding dengan higienitas botol susu yang baik. Kata-kata kunci:higienitas botol susu, diare, Puskesmas Kelayan Timur

Background: Stenochlaena palustris, also known as kelakai or lemidi, is frequently linked to anti-inflammatory, anti-bacterial, anti-fungal, and antioxidant properties. S. palustris phytosterols are suggested to suppress the progression of breast cancer. Objective: The objective of this study is to evaluate the potential of phytosterols found in S. palustris to act as estrogen receptor (ER) inhibitors. Methods: Phytosterols (alpha-tocopherol, beta-sitosterol, campesterol, stigmasterol, fucosterol) were docked to estrogen receptor (PDB ID: 7KBS). Molecular docking parameters included Gibb's free energy and interactions between ligand and protein. ADMET properties were analyzed using pkCSM and SwissADME. Results: Alpha-tocopherol showed the highest interaction with the estrogen receptor with ΔG value -8. 9254 kcal/mol (the native ligand, raloxifene, had a G value of -12.052 kcal/mol). Leu387 (hydrogen bond); Phe404 (Phi-phi-T shaped), Leu391, Leu346, Trp383, Leu354, Ala350, Leu525, Leu349 (Alkyl) were among the residues by which a-tocopherol interacted with ER. Alpha-tocopherol has no hepatotoxicity and no skin sensitization. Conclusion: By suppressing ERa, phytosterols from S. palustris may have potential anti-breast cancer activity and may be used to prevent estrogen-dependent human cancers like breast cancer.