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The mechanisms of anti-tumor action of low intensity factors of activation therapy remain little investigated. The aim of the present paper is to study the changes in the immune system organs, the state of blood leukocytes and tumor area under effective activation therapy in tumor-bearing animals using EMR microwave range. The research is relevant due to the immune processes influence on cardiovascular system performance. Materials and methodsIn experiments on 77 albino outbred male rats with inoculated sarcoma-45 and Pliss lymphosarcoma tumors low intensity EMR of microwave and EHF ranges with bioeffective frequencies has been used as an activation therapy factor. The structural-functional changes in the immune system organs, some indices of blood leukocyte activity, composition of immune cells infiltrating tumors when inhibiting their growth and regression have been studied. Besides, the signs of intercellular interactions with participation of leukocytes in the tumor area have been considered. ResultsThe pronounced anti-tumor effects in the studied EMRs are re-

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