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The main role in atherosclerotic damage of the vascular wall is given now to the inflammatory process, the development of which is facilitated by a variety of risk factors (RF). Many of these factors begin to affect on the cardiovascular (CV) system in youth and even in childhood. Some authors refer to RF infectious-inflammatory diseases (IID), which were transferred earlier. The aim is to evaluate some parameters of vascular status in young people in the presence of such focal infection (FI) as chronic decompensated tonsillitis (CDT). Material and methods. Within the main group, 52 young patients aimed at performing surgery due to the presence of IID (age from 18 to 27 years) were examined. 76 persons of comparable sex, age and profile of the main RF without any IID were served as control. The control group was formed from the number of students according to the results of the annual preventive examination in the framework of the Federal Program "University of healthy lifestyle". Both groups were quite comparable in age, sex and profile of the main RF. In addition to the assessment RF-profile it was carried out the determination of indicators of the central pressure and vascular stiffness with the help of hardware-diagnostic complex BPLab ("Petr Telegin", Nizhny-Novgorod, Russia) with the use of programs set Vasotens Office. This program involves an in-depth contour analysis of the properties of pulse waves at the level of both the aorta and peripheral arteries. Statistical processing was carried out using the software "Statistica 10.0" (StatSoft Inc, USA). Results: It was found that in the main group compared with the control group, the pulse wave propagation velocity in the aorta PWVao equal to 10.61±0.25 versus 9.73±0.15 m/s (p=0.004), the augmentation index in the aorta AIxao was 3.88±0.31 versus -1.04±0.08%. In discussing two groups augmentation index in the brachial artery AIx made up of 32.15±2,70 against -48,89±1,52% (p=0.05), arterial augmentation index, AIx normalized to heart rate heart rate was equal to -35,23±vs -49,67 of 5.39±2.56%. In this case, the values of both peripheral and aortic SBP, DBP, Medium BP and Puls BP in patients with DHT were slightly lower than in persons of the control group. Conclusion: The data of the youth study of the dense-elastic vascular potential in different parts of the arterial bed showed a marked increase in vascular rigidity from both the peripheral arteries and the aorta in presence of CDT. In this case, aortic remodeling was more pronounced. It is useful to consider these findings in process of planning and implementing individualized prevention programmes among young people, taking into account the availability of FI.

Аннотация. Проведено комплексное функциональное исследование сердечно-сосудистого статуса у молодых стационарных пациентов с хроническим тонзиллитом, подлежащих оперативному вмешательству. Основную группу составили 52 молодых больных декомпенсированным тонзиллитом и в контрольную группу включены 76 юношей и девушек без наличия каких-либо очаговых инфекционных заболеваний. Кроме оценки профиля основных факторов риска, осуществляли определение показателей центрального давления и сосудистой жёсткости с помощью диагностического комплекса BPLab (ООО «Петр Телегин», Н-Новгород) на основе программного обеспечения Vasotens Office. Данные обработаны с помощью пакета программ «Statistica 10.0» (StatSoft Inc, USA). Результаты изучения плотноэластического потенциала на разных участках артериального ложа показали заметное повышение сосудистой ригидности со стороны как периферических артерий, так и аорты. При этом аортальное ремоделирование оказалось более выраженным. Выявлены также признаки некоторого снижения сократительной функции миокарда. Полученные данные полезно учитывать при планировании молодёжной диспансеризации и осуществлению индивидуализированных профилактических программ среди обсуждаемого студенческого контингента. Ключевые слова: очаговая инфекция, сосудистая ригидность, молодой возраст. Annotation. The complex functional study of the vascular status in young patients with decompensated chronic tonsillitis, aimed at surgical intervention, was organized. The main group consisted of 52 patients with decompensated tonsillitis and the control group included 76 boys and girls without any focal infectious diseases. It was carried out the determination of indicators of the Central Pressure and vascular stiffness with the help of a diagnostic complex BPLab («Petr Telegin», Nizhny Novgorod) on the basis of software Vasotens Office. The data was processed using «Statistica 10.0» software package (StatSoft Inc, USA). Results of the study of the density-elastic potential at different levels of the arterial bed showed a marked increase in vascular rigidity from both the peripheral arteries and the aorta. But aortic remodeling was more pronounced. The signs of some decrease in myocardial contractile function are also revealed. The obtained data is useful for planning of youth medical examination and implementation of individualized prevention programs among the young men.

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