ВПЛИВ ЕКСТРАКТУ ЛИСТЯ ПЕРСИКА НА СТАН МЕТАБОЛІЧНИХ ПРОЦЕСІВ ТА ПРООКСИДАНТНО/АНТИОКСИДАНТНИЙ БАЛАНС ЩУРІВ В УМОВАХ ХРОНІЧ-НОГО ІММОБІЛІЗАЦІЙНОГО СТРЕСУ

The economic and political processes taking place in the southern Far East have had a significant impact on the development of the territorial structure. Methodologically, a constructive and comprehensive geopolitical approach was used that allowed a structural evaluation of economic and political realities and their impact on the formation and development of the territorial structure, as well as its various orientations and typologies in the south of the country. Far East. In addition, its focused study allowed to evaluate the economic and political effect of the modernization scenario, to analyze the impact of external and internal economic, political and social realities with a focus on the restructuring and organization of the territorial structure, all of which allowed to identify the main problems of its destabilization and, at the same time, determine the prospects for further growth of the elements of the system to varying degrees, affecting the industrial, transportation, infrastructure and other spheres of the population's life. It is concluded that the dialectical interaction of a set of political and economic realities of transformations and modernizations, internal and external, have configured an arial-nodal / linear-nodal polycentric linear structure in the south of the Far East.

The objective of the scientific and practical research is to assess the economic effect of choosing a scenario for the innovative development of the pilot production of an aerospace enterprise based on modernization and creation of a public-private partnership. The study reveals the innovative potential of physically and morally obsolete production of complex metalworking, the expansion of industrial integration within the enterprise and in the foreign market. Economic modeling of increasing efficiency was carried out by modernizing the enterprise’s production following two innovative scenarios, affecting production technologies, business processes, investments, and the organizational structure to different degrees. A methodological approach to achieving this goal provides a scenario-based assessment of the direct economic effect of the pilot production of an enterprise when introducing innovations different in their focuses, duration, and cost. An innovative model has been developed to present production development scenarios with a focus on internal or external factors, on flexibility or on stable development. Assessment of the current level of technological development and economic efficiency of pilot production made it possible to determine the possibilities of managerial and technological innovative development of a nationally significant enterprise; to determine the direct economic effect of modernization and production integration of participants in the innovation process. The degree of the economic effect directly depends on the chosen innovative scenario and the scale of its implementation in the enterprise.  

Growth of financial activity, stable functioning and sustainable development of economic systems are largely ensured by the formation of strong and competitive business structures that timely adapt their strategic approaches to management in accordance with the conditions of the environment. Maintaining competitive positions in the market in conditions of digitalization becomes difficult or impossible without creating new sources of competitive advantages. Digitalization of the economy and business requires a corresponding change in the business model of the organization. One of the most contemporary issues of improvement in the structure of the business model is the system of interaction with the client. Its timely transformation ensures an integrated system approach to service and interaction with the client based on the omnichannel approach. This approach means including into the business processes of organizing a comprehensive system of digital and analog communication channels that provide multi-channel communication of business with the client, which form a single history of contacts and client experience in the company. From this position, the number of mastered, implemented digital technologies and communication channels in the system of interaction with the client can serve as an indicator of the company’s digital activity. There is proposed an author's approach to transforming the system of interaction with the client (through the omnichannel prism) in the business model of the organization in the context of the digitalization of the economy and business, defines the requirements for the business model and developed a system of indicators for assessing its effectiveness. An algorithm for introducing a digital business model into the activities of a trading enterprise is developed.

The objective of the logging campaign was to explore the hydrocarbon deposits in low-permeability clastic reservoirs utilizing an advanced logging suite and a high-tech wireline formation tester (WFT). The exploration well, which had a diameter of 146 mm and was drilled to a vertical depth of 4750 m, had a temperature of 147 degrees Celsius downhole. Despite the challenging geological and downhole conditions: low permeability reservoir, high reservoir temperature, small wellbore diameter, and very high salinity drilling mud, the advanced logging suite data, which included nuclear magnetic resonance (NMR) and cross-dipole broadband acoustic logging, was successfully acquired. The WFT, which consists of a unique radial probe technology for efficient sampling of extremely low-permeability formations and a downhole fluid analyzer to determine the nature of the inflow and make rapid operational decisions in real time, was then used to perform downhole fluid analysis and sampling stations. Oil and gas-saturated reservoir intervals were identified, their porosity, water saturation, and permeability were evaluated, and an optimal open hole WFT program was produced as a result of the extended logging suite's interpretation. Special technological operations were performed during well logging in this well, allowing for the acquisition of high-quality NMR data under extreme conditions. Rapid processing and interpretation of well logging data, performed without any a priori reservoir data, allowing for the identification of the best permeability intervals in oil and gas-saturated reservoirs and the design of an optimal WFT program in an open hole. Downhole fluid analysis and sampling stations were performed with WFT with pressure build-up to determine fluid mobility to validate the presence of productive intervals. Thus, in several downhole trips in a relatively short period of time, potential hydrocarbon layers were assessed in an open hole section, and in the presence of sufficient fluid mobility, the saturation of the interval was determined by WFT. It is important to note that downhole gas samples were acquired in intervals having fluid mobility less than 0.06 mD/cP, where the conventional well test would most probably fail to induce a flow without stimulation. An integrated approach using modern well logging methods made it possible to solve the set geological challenges in the extreme conditions in this exploration well, where traditional methods would introduce significant uncertainties.