Human Rights and the Ethics of Globalization Human Rights and the Ethics of Globalization provides a balanced, thoughtful discussion of the globalization of the economy and the ethical considerations inherent in the many changes it has prompted. The book's introduction maps out the philosophical foundations for constructing an ethic of globalization, taking into account both traditional and contemporary sources. These ideals are applied to four specific test cases: the ethics of investing in China, the case study of the Firestone company's presence in Liberia, free trade and fair trade issues pertaining to the coffee trade with Ethiopia, and the use of low-wage factories in Mexico to serve the U.S. market. The book concludes with a comprehensive discussion of how to enforce global compliance with basic human rights standards, with particular attention to prospects for stopping abuses by multinational corporations through litigation under the Alien Tort Claims Act.
Endovascular embolization of cerebral aneurysms is a common approach for reducing the risk of often‐fatal hemorrhage. However, currently available materials used to occlude these aneurysms provide incomplete filling (coils) or require a complicated, time‐consuming delivery procedure (solvent‐exchange precipitating polymers). The objective of this work was to develop an easily deliverable in situ forming hydrogel that can occlude the entire volume of an aneurysm. The hydrogel is formed by mixing a solution of a temperature‐responsive polymer containing pendent thiol groups (poly(NIPAAm‐co‐cysteamine) or poly(NIPAAm‐co‐cysteamine‐co‐JAAm)) with a solution of poly(ethylene glycol) diacrylate (PEGDA). Incorporation of hydrophilic grafts of polyetheramine acrylamide (JAAm) in the temperature‐responsive polymer caused weaker physical crosslinking, facilitated faster and more complete chemical crosslinking, and increased gel swelling. One formulation (30 wt % PNCJ20 + PEGDA) could be delivered for over 220 s after mixing, formed a strong and elastic hydrogel (G' > 6000 Pa) within 30 min and once set, maintained its shape and volume in a model aneurysm under flow. This gel represents a promising candidate water‐based material utilizing both physical and chemical crosslinking that warrants further investigation as an embolic agent for saccular aneurysms.
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