This qualitative research aims to analyze students' cognitive structure of acid base topics through flowmap methods use Learning Cycle 8E model. The subjects of this study were 36 students of XI MIA 4 SMA N 54 Jakarta. Data were collected through achievement test, interview, flowmap, class observation, reflective journal and students' worksheet. The results showed that students build their cognitive structure based on students' understanding and experience. Learning Cycle 8E model has had an impact on the development of students' cognitive structure and softskill. Based on the results of the study, it is seen that percentage of students who experienced misconception decreased and the percentage of students who understand increased. This proves that Learning Cycle 8E model can overcome student misconception. Learning Cycle 8E model also affects the development of student softskill. Based on the results of the research, it was found that students' have applied the attitude of respecting and appreciating when dealing with differences of opinion.