A facile one-pot synthesis of 5-benzoyl-6-methylthio-1,2,3,4-tetrahydropyrimidines in good yields is reported.

1-(Aralkyl/aryl)-3-(alkyl/aralkyl)-5-aroyl-1,2,3,4-tetrahydropyrimidines (2a-c) have been synthesized by dethiomethylation of 5-aroyl-6-methylthio-1,2,3,4-tetrahydropyrimidines (1 a -c). An alternative one-pot synthetic strategy has been developed for the title compounds 2a-t by the reaction of enaminones 3 with primary amine and formaldehyde in refluxing methanol in good yields.

Microwave chemistry O 0170 An Efficient, Microwave Assisted Solvent-Free Synthesis of Polarized Enamines. -This newly found method is reported to be solvent-free, environmentally friendly, to have short reaction times and to give good to excellent yields. -(CHANDA, K.; DUTTA, M. C.; KARIM, E.; VISHWAKARMA*, J. N.; J. Indian Chem. Soc. 81 (2004) 9, 791-793; Org. Res. Lab.,

Ketones Q 0350A Facile Route to Enaminones: Synthesis of 3-Alkyl/Aralkyl/Arylamino-1-arylprop-2-en-1-ones. -A facile synthetic pathway to title compounds (III) and (V) by the reaction of 3-dimethylamino-1-arylprop-2-en-1-ones (I) with aromatic and aliphatic amines is reported. For the latter the reaction is accelerated by microwave irradiation.-(DUTTA, M. C.; CHANDA, K.; KARIM, E.; VISHWAKARMA*, J. N.; Indian J.

A Facile One-Pot Synthesis of Novel Substituted 1,2,3,4-Tetrahydropyrimidines. -The reaction of title compounds (IV) are with hydrazinehydrate to give anellated pyrazoles fails. -(KARIM, E.; KISHORE, K.; VISHWAKARMA*, J. N.; J. Heterocycl. Chem. 40 (2003) 5, 901-903; Dep. Chem., St. Anthony's Coll., Shillong 793 001, India; Eng.) -C. Oppel