Human immunodefiiency virus (HIV) infection and aquired immunodeficiency syndrome (AIDS)cause a progressive depletion of CD4 + T cell populations accompanied by progressive impairment of cellular immunity and increasing susceptibility to opportunistic infections. Seborrheic dermatitis is one of the most common skin opportunistic infections on HIV/AIDS patients. Malassezia species is bilieved as the causative of seborrheic dermatitis. The aim of the study was to evaluate low CD4 + T cell counts as risk factor for Malassezia sp. infection in HIV/AIDS patients. This was an observational study with cross-sectional design conducted on HIV/AIDS patients who attended in Department of Dermatology and Venereology, Faculty of Medicine Universitas Gadjah Mada/ Dr Sardjito General Hospital, Yogyakarta and met the inclusion and exclusion criteria. Culture of Malassezia sp. was conducted in Department of Microbiology and classified as high (>100 CFU/ tape) and low (<100 CFU/tape) density colonies. CD4 Sci, Volume 46,No. 4, CFU/tape. Tidak ada hubungan bermakna adalah kadar sel T CD4 + dengan jumlah koloni Malassezia sp dalam penelitian ini (p=0,607; 95%CI=0,(4)(5)19; RP=0,452). Dapat disimpulkan, kadar sel T CD4 + yang rendah bukan merupakan faktor terjadinya infeksi Malassezia sp. pada penderita HIV/AIDS.

Human immunodefiiency virus (HIV) infection and aquired immunodeficiency syndrome (AIDS)cause a progressive depletion of CD4 + T cell populations accompanied by progressive impairment of cellular immunity and increasing susceptibility to opportunistic infections. Seborrheic dermatitis is one of the most common skin opportunistic infections on HIV/AIDS patients. Malassezia species is bilieved as the causative of seborrheic dermatitis. The aim of the study was to evaluate low CD4 + T cell counts as risk factor for Malassezia sp. infection in HIV/AIDS patients. This was an observational study with cross-sectional design conducted on HIV/AIDS patients who attended in Department of Dermatology and Venereology, Faculty of Medicine Universitas Gadjah Mada/ Dr Sardjito General Hospital, Yogyakarta and met the inclusion and exclusion criteria. Culture of Malassezia sp. was conducted in Department of Microbiology and classified as high (>100 CFU/ tape) and low (<100 CFU/tape) density colonies. CD4 Sci, Volume 46,No. 4, CFU/tape. Tidak ada hubungan bermakna adalah kadar sel T CD4 + dengan jumlah koloni Malassezia sp dalam penelitian ini (p=0,607; 95%CI=0,(4)(5)19; RP=0,452). Dapat disimpulkan, kadar sel T CD4 + yang rendah bukan merupakan faktor terjadinya infeksi Malassezia sp. pada penderita HIV/AIDS.

Background Psoriasis is a chronic inflammatory skin disease with a strong genetic predisposition and autoimmune pathogenic traits. Psoriasis vulgaris is also called plaque-type psoriasis, and is the most prevalent type. Psoriasis vulgaris is chronic inflammatory disease and characterized by periods of attack and remission. The chronicity of psoriasis vulgaris can affect patient’s quality of life. Case presentation A 33-year-old male came to Unggul Karsa Medika Hospital’s outpatient department with itchy, scaly, red plaques all over his body except his palms, soles, and face. The patient went to the dermatologist because his symptoms were getting worse and worse. Dermatologic examination concludes the lesions as multiple, generalized, discrete, circumscriptive, elevated, dry, regular-discoid erythematous plaques with psoriasiform scales located at the patient’s head, ears, nape, back, chest, belly, both arms and legs. Conclusion The diagnosis of psoriasis vulgaris was made based on history and clinical symptoms, supported by histopathological results. Treatment optimization and transitioning for moderate-to-severe plaque psoriasis include methotrexate or cyclosporine, along with topical therapy and supportive therapy.