Sickle-cell anemia (Sickle-cell anemia) is a disease characterized by the presence of abnormal red cells (sickle-shaped) that are removed from the circulation and destroyed by an inherited genetic disorder due to a mutation of the gene encoding the amino acid valine, transcribing an altered hemoglobin. The objective of the research is to verify the main means used for the laboratory diagnosis of sickle cell anemia and the carriers of these traits, as well as to perform an analysis of the literature related to the educational strategies on genetic counselingadded in the Unified Health System (SUS), especially in Attention Basic. An exploratory, descriptive research was carried out through a bibliographic review. The databases consulted were Virtual Health Library - VHL and SciELO - Scientific Electronic Library, where the existence of articles, dissertations, theses related to the subject were verified. It is observed that although there is a vast literature on Sickle Cell Anemia, there is little recent research in the databases used for this research related to the Diagnostics and educational strategies adopted in the Unified Health System (SUS), Anemia and genetic counseling.

JUSTIFICATIVA E OBJETIVOS: A doença oncológica per se é uma condição que muitas vezes influencia no tratamento dispensado ao paciente. O objetivo do presente estudo foi comparar o desfecho hospitalar de pacientes oncológicos e não oncológicos submetidos à procedimentos cirúrgicos eletivos com alto risco de óbito. MÉTODO: Estudo de coorte prospectivo observacional, realizado em UTI de hospital terciário no período de 01 de abril a 31 de julho de 2005. Foram coletados dados demográficos, escore APACHE II, MODS,

Hydroxyurea (HU) is the most important advance in the treatment of patients with sickle cell disease (SCD). Sickle cell disease is a debilitating and hereditary disease most common in Brazil and worldwide, with a predominance of black people. The aim of this study was to analyze the importance, benefits and adverse reactions of using hydroxyurea in the treatment of sickle cell anemia through a literature review. The research was conducted through bibliographic analysis by the literature review method performed in the Latin American and Caribbean Health Sciences Information System (LILACS), Scientific Electronic Library Online (SCIELO) databases. The following descriptors were used to survey the articles: Hydroxyurea, Sickle Cell Anemia, Sickle Cell Disease, articles published between 2006 and 2016 in Portuguese language were selected. Thus, 13 articles, through content analysis, were built four analytical categories: Characterization of sickle cell anemia, Benefits expected in the treatment with the use of UH, Criteria used for treatment with UH, Adverse reactions to UH. UH brings a quality of life for the patient as it reduces the number of hospitalizations and length of stay, decreases blood transfusions, reduces painful crises and occurrences of Acute Thoracic Syndrome (STA), minimizes splenic seizures and possible seizures. acute neurological events, generates regression or stabilization of organ damage, reducing the mortality of these patients by up to 40%.