Este estudo teve como objetivo traçar o perfil do ensino de gestão nos cursos de graduação em Odontologia no Brasil. Caracteriza-se como pesquisa transversal com abordagem quantitativa a partir de dados secundários. A amostra foi composta por 327 Instituições de Ensino Superior (IES) que possuem cursos graduação em Odontologia cadastrados no Ministério da Educação. A coleta ocorreu a partir de consultas aos sítios web das IES, dos quais foram analisadas as matrizes curriculares dos cursos de Odontologia e ementas, e observada a existência de componentes curriculares que abordassem o ensino de gestão. Quando presentes, foram colhidas as seguintes informações: região da IES, categoria administrativa da IES, natureza do componente curricular, semestre ofertado, carga horária, metodologia empregada e nomenclatura. Dos 327 cursos de graduação em Odontologia pesquisados, apenas 27,83% ofertam o ensino de gestão em suas matrizes curriculares. A maioria dos componentes curriculares é de natureza obrigatória (74,72%), ofertadas predominantemente no 8° (25,28%) e 9° (24,17%) semestres, com a carga horária variando entre 31 e 60 horas de aulas (79,12%) e natureza teóricas (60,31%). Assim, concluiu-se que o ensino de gestão é pouco explorado pelos cursos de graduação em Odontologia no Brasil, fazendo-se necessária a sua inclusão nas matrizes curriculares a fim de preparar o cirurgião-dentista para atuar na área da gestão em saúde.
Objective: To investigate the antifungal potential of A. colubrina, and its phytochemical characteristics, thermal profile and toxicity. Material and Methods: To assess potential antifungal activity, the technique of microdilution was used with the determination of the Minimum Inhibitory Concentration and Minimum Fungicidal Concentration, using standard species of Candida and recent clinical isolates of Candida albicans. Analyses of action of the extract were performed on the wall and cell morphology of C. albicans, of the interactive effect between the plant extract and nystatin on C. albicans through the checkerboard method, and of growth kinetics. The phytochemical screening was determined by spectrophotometry. The thermal profile was traced with the determination of thermogravimetric curves (TG) and differential scanning calorimetry (DSC). The toxicity was evaluated by the method of hemolysis. Results: The extract of A. colubrina showed a fungistatic potential against all bacteria tested and it acted by modifying the cellular morphology of C. albicans. There was a synergism between nystatin and the plant extract (FIC=0.375), and 53.18% of total polyphenols were determined. The TG curve showed the occurrence of three steps of thermal decomposition. None of the tested concentrations became the effective cytotoxic concentration. Conclusion: Further studies should be conducted to understand the efficacy and the mechanisms of action involved in the antifungal activity of the plant extract of A. colubrina in order to produce a new drug for the treatment of oral candidiasis.
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