Extensive PVPs have not previously been described in a golden retriever dog or previously reported to cause pruritus in dogs. Due to the large skin area involved, surgical excision was not feasible in this case. However, two rounds of treatment using laser were completely curative for both focal pedunculated and plaque-like PVP lesions. Additionally, compared to surgical excision, laser treatment is expected to result in less postoperative discomfort, reduced surgery time and fewer postoperative infections. This is the first report of successful treatment of canine PVPs using a CO2 laser. The success of this treatment in this case suggests that laser provides an excellent treatment option for extensive PVPs in dogs.

Although CEG appears to be an uncommon disease, it should be included as a differential diagnosis for dermal, nodular lesions affecting the digits. Chlorambucil appears to be an effective and well tolerated prednisolone sparing agent for treatment of CEG. Carbon dioxide laser ablation appears to be an effective method of debulking CEGs.

Lasalocid was not identified in the receptor fluid of any sample, indicating that systemic absorption of the active ingredient in vivo is unlikely. Lasalocid may be useful in the treatment of MRSP infections if in vivo studies support safety and efficacy.