An experimental study of Rayleigh-Be'nard convection in helium gas at roughly 5 K is performed in a cell with aspect ratio 1. Data are analysed in a ' hard turbulence ' region (4 x 10' < Ra < 6 x 10l2) in which the F'randtl number remains between 0.65 and 1.5, The main observation is a simple scaling behaviour over this entire range of Ra. However the results are not the same as in previous theories. For example, a classical result gives the dimensionless heat flux, Nu, proportional to R d while experiment gives an index much closer to 5. A new scaling theory is described. This new approach suggests scaling indices very close to the observed ones. The new approach is based upon the assumption that the boundary layer remains in existence even though its Rayleigh number is considerably greater than unity and is, in fact, diverging. A stability analysis of the boundary layer is performed which indicates that the boundary layer may be stabilized by the interaction of buoyancy driven effects and a fluctuating wind.
In a process called "molecular combining," DNA molecules attached at one end to a solid surface were extended and aligned by a receding air-water interface and left to dry on the surface. Molecular combing was observed to extend the length of the bacteriophage lambda DNA molecule to 21.5 +/- 0.5 micrometers (unextended length, 16.2 micrometers). With the combing process, it was possible to (i) extend a chromosomal Escherichia coli DNA fragment (10(6) base pairs) and (ii) detect a minute quantity of DNA (10(3) molecules). These results open the way for a faster physical mapping of the genome and for the detection of small quantities of target DNA from a population of molecules.
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