During the course of figure preparation for the above article, we inadvertently redisplayed images from Figure 2G in Figure 5H. The corrected Figure 5 is provided below. Figure 5H demonstrates the ability to generate neuron-specific class III b-tubulin (TUJ1; green) and tyrosine hydroxylase (TH; red) expressing neurons from the genetically corrected Parkinson's disease patient-derived hiPSCs, and the corrected figure does not affect the description of the results in the paper or the conclusions drawn. We regret our error and apologize for any inconvenience it may have caused.

The paper describes the effect of the isotopic mass on plasma parameters as observed in the ASDEX tokamak. The paper comprises Ohmic as well as L mode, H mode and H* mode scenarios. The measurements reveal that the ion mass is a substantial and robust parameter, which affects all the confinement times (energy, particle and momentum) in the whole operational window. Both core properties such as the sawtooth repetition time and edge properties such as the separatrix density change with the isotopic mass. Specific emphasis is given to the edge parameters and changes of the edge plasma due to different types of wall conditioning, such as carbonization and boronization. The pronounced isotope dependences of the edge and divertor parameters are explained by the secondary effect of different power fluxes into the scrape-off layer plasma and onto the divertor plates. Finally, the observations serve to test different transport theories. With respect to the ion temperature gradient driven turbulence, the isotope effect is also studied in pellet refuelled discharges with peaked density profiles. The results from ASDEX are compared with the results from other experiments

High fusion power experiments using DT mixtures in ELM-free H mode and optimized shear regimes in JET are reported. A fusion power of 16.1 MW has been produced in an ELM-free H mode at 4.2 MA/3.6 T. The transient value of the fusion amplification factor was 0.95±0.17, consistent with the high value of nDT(0)τEdiaTi(0) = 8.7 × 1020±20% m-3 s keV, and was maintained for about half an energy confinement time until excessive edge pressure gradients resulted in discharge termination by MHD instabilities. The ratio of DD to DT fusion powers (from separate but otherwise similar discharges) showed the expected factor of 210, validating DD projections of DT performance for similar pressure profiles and good plasma mixture control, which was achieved by loading the vessel walls with the appropriate DT mix. Magnetic fluctuation spectra showed no evidence of Alfvénic instabilities driven by alpha particles, in agreement with theoretical model calculations. Alpha particle heating has been unambiguously observed, its effect being separated successfully from possible isotope effects on energy confinement by varying the tritium concentration in otherwise similar discharges. The scan showed that there was no, or at most a very weak, isotope effect on the energy confinement time. The highest electron temperature was clearly correlated with the maximum alpha particle heating power and the optimum DT mixture; the maximum increase was 1.3±0.23 keV with 1.3 MW of alpha particle heating power, consistent with classical expectations for alpha particle confinement and heating. In the optimized shear regime, clear internal transport barriers were established for the first time in DT, with a power similar to that required in DD. The ion thermal conductivity in the plasma core approached neoclassical levels. Real time power control maintained the plasma core close to limits set by pressure gradient driven MHD instabilities, allowing 8.2 MW of DT fusion power with nDT(0)τEdiaTi(0) ≈ 1021 m-3 s keV, even though full optimization was not possible within the imposed neutron budget. In addition, quasi-steady-state discharges with simultaneous internal and edge transport barriers have been produced with high confinement and a fusion power of up to 7 MW; these double barrier discharges show a great potential for steady state operation. © 1999, Euratom

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A record performance on JET has been obtained with shear optimization scenarios. A neutron yield of 5.6 × 10 16 s −1 in deuterium discharges, and a global energy confinement improvement above the ITER-89 L-mode scaling with H 2.5 in L-mode and H 3 in H-mode have been achieved. The tailoring of plasma current, density and heating power waveforms and current profile control with lower hybrid current drive and ICRF phasing have been essential. Internal energy, particle and momentum transport barriers develop spontaneously upon heating above a threshold power of about 15 MW with neutral beams and ICRH into a low-density target plasma, with a wide central region of slightly negative or flat magnetic shear with q > 1 everywhere. An additional H-mode transition can also raise the pressure in the region between internal and edge transport barriers. The ion heat conductivity falls to the neoclassical level in the improved core confinement region. Pressure profile control through power deposition feedback control makes it possible to work close to the marginal stability boundary for pressure-driven MHD modes. First experiments in deuterium/tritium plasmas, with up to 75% tritium target concentration, have established internal transport barriers already with heating powers at the lowest threshold of pure deuterium plasmas, resulting in a fusion power output of P fusion = 2 MW.