The aim of the present study was to evaluate some potential therapeutic effects of peel and pulp of two eggplant varieties (round black and long white) which are widely consumed among Egyptian people using experimental rats. Peel and pulp samples were analyzed to determine the chemical composition and some minerals (Na, K and Fe). Total phenols content also were determined in addition to the identification of phenolic compounds by HPLC. The dried peel and pulp of two eggplant varieties were supplemented as 15% to the diet and used for treating diabetic, hypertensive, and hyperlipidemic rat. Thirty male albino rats weighing 140±10 g were divided to 6 groups (5 rats in each group). Five groups were given 10% fructose in the drinking water for 6 weeks to induce hypertension, hyperlipidemia and hyperinsulinemia. At the end of the experiment, Serum glucose, insulin, total cholesterol, triglycerides, lipoprotein fractions, blood pressure, serum Na, K, and MDA levels were determined in rats serum. In addition the kidney and liver of rats were removed after ether anaesthetesia and making histopathological examination. Briefly, different tested eggplant types can be considered as a good healthy food which can prevent and improve the status of hyperglycemia, hyperlipidemia, and hypertension. Peel of round black eggplant was more effective for lowering hyperlipidemia and hypertension and improved lipid profile, while the long white type was more effective for lowering hyperglycemia. These healthy effects of eggplant can be attributed to its good content of fibers, phenolic compounds, and potassium. Furthermore, the eggplant has the ability to bind with bile acids and inhibiting the activity of some enzymes as αglucosidase and angiotensin converting the enzyme which increases hypertension.

Cholesterol Cholesterol and basal diet constituents were obtained from El-Gomhoria Company for Trade of Drugs, Chemicals and Medical Equipments, Cairo, Egypt. Methods Basal diet: The basal diet was prepared of the following: Protein (10%), corn oil (10%), vitamin mixture (1%), mineral mixture (4%), choline chloride (0.2%), methionine (0.3%), cellulose (5%), and the remained is corn starch (69.5%) according to Campbell (1963). While the salt mixture was formulated according to Hegested et al., (1941). Cholesterol containing diet was prepared by adding 1% cholesterol to the basal diet for 3 weeks to induce hypercholesterolemia. Experimental Design: Fifty male albino rats were housed in healthy condition (21-23ºC) and fed on basal diet for one week before starting the experiment for acclimatization , after this, rats were divided into two main groups, the first main group (5 rats) fed on basal diet as a negative control (ve-) and the other main group (45 rats) was fed on 1% cholesterol+ 0.02 salts for 3 weeks to induce hypercholesterolemia, then classified into nine sub groups as follow: Group (2): Positive control group (untreated group) Group (3): Treated with 5% milled Apricot Peels (AP).

This work was conducted to study the effect of Jojoba oil, lavender oil and their mixture on hypercholesterolemic rats. Thirty five male albino rats, weighing (150±10g), were divided into 7 groups (5 rats each) , 25 of them fed on1.5% cholesterol+0.2% bile salts to induce hypercholesterolemia The first main group fed on basal diet as a negative control group. One of the second hypercholesterolemic main group (5 rats) fed on basal diet as apositive control group , and the other hypercholesterolemic rats fed on basal diet and treated by Jojoba oil, lavender oil (2.5% and 5%) and mixture of them 2.5% for 4 weeks. At the end of the experiment serum samples were analyzed for the following parameters: Lipid profile; total cholesterol (T.C), total bilirubin, tri-glycerides (T.G), high density lipoprotein (HDLc), low density lipoprotein (LDLc), very low density lipoprotein (VLDLc) ; urea , creatinine , uric acid ; glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), alkaline phosphatase (ALP) and glucose. At the same time, the organs: Heart, kidney, liver, lungs and spleen were removed for weghting. The results indicated that treating rats with Jojoba oil, lavender oil and mixture of them decreased serum glucose, creatinine, uric acid, ALT, AST and ALP, as compared to the positive control group. It was concluded that the diet of Jojoba oil, lavender oil and mixture of them led to a significant decrease in lipid fractions ; (T.C),(T.G),(LDLc),(VLDLc) With increase of (HDL) , and these treatment are recommended to reduce the level of lipid profile for the patients with hypercholesterolemia.

This study was conducted to investigate the protective effect (at level 7.5% of marrow vegetable, lettuce seed, prickly pear seeds) and mixture of them at 1:1:1ratio on liver and kidney functions, blood lipid profiles and blood sugar in rats fed with diets contain height level of cholesterol. Thirty mature albino male rats weighing 150 + 5 g. B.WT. each, were divided into sex equal groups, The first group kept as a control-ve group, while the others five groups fed on diet containing high level of cholesterol for 3 weeks to obtain hypercholesterolemic rats. At the end of experimental period (28 days), animals were sacrificed. Blood samples were collected to determine the biochemical analytics: serum total cholesterol (T.C.), triglycerides (T.G), lipoprotein fractions (HDL-c, LDL-c, and VLDL-c), atherosclerotic index (AI), liver enzymes (AST, ALT and ALP), total bilirubin, urea, uric acid, creatinine and fasting plasma glucose. Moreover, heart, liver and kidneys subjected to for histopathological examination. The obtained results concluded that diets of marrow, lettuce, prickly pear seeds and their mixture caused the improvement of all biochemical analysis.

The present study aimed to assess the effect of low phosphorus and potassium diets in comparison with sevelamer carbonate (SC) medication which does the same effect. Fortyeight male albino rats weighing 280 ± 10g were randomly classified into six groups (8 rats each) The first group served as a negative control group, fed on a basal diet only. The other five groups were fed on a basal diet containing 0.25% w/w adenine daily for 35 days to induce renal failure Then, rats reclassified into 5 groups which were positive control and treated rat groups that were sevelamer carbonate medication 1000 mg/kg/day, the rest of the three subgroups of rat fed experimental diet containing 25, 50 and 75% of their low nutritional needs of phosphorous and potassium. The treatment period is designed for twelve weeks. Results showed that feeding RF rats with 25, 50 and 75% of RPK prevent the increase in hyperphosphatemia and hyperkalemia. The results revealed that levels of fibroblast growth factor 23 enzyme, parathyroid hormone, renin enzyme and insulin intolerance were decreased compared with the negative group and RF rats treated with SC. Subsequently, improvement in the kidney functions of all treated groups were exhibited. In conclusion, feeding with 50% of RPK is effective in improving kidney functions in renal failure rats.