To define the prevalence of Molar Incisor Hypomineralization (MIH) in Brazil since the reports ranged from 2.5% to 40.2%. Material and Methods: We studied 407 children from 7 to 14 years of age. MIH was measured using the European Academy of Paediatric Dentistry criteria of 2003. Clinical data were collected by a calibrated dentist (Kappa=0.88) and included affected teeth and degree of MIH severity (mild/severe). Mild MIH cases were considered when the tooth presented demarcated opacity ≥ 1.0mm, without any loss of structure. While severe cases were defined by teeth in which loss of structure was present, or past or current lesion that required treatment, or presence of atypical restorations. In addition, published data (nine studies) reporting MIH in Brazilians were identified, and the heterogeneity of these studies was tested (I2 index/ p≤0.01). Results: In the original sample studied, the majority of patients were males (55.3%; n = 225), with an average age of 10.1 years (± 2.1 years). The prevalence of MIH in this group was 14.5% (59 affected in 407), and most of the affected teeth had a mild degree of alteration (77.4% or 202 in 261 teeth). Conclusion: A meta-analysis including nine published reports, and our original data showed that MIH prevalence in Brazil is 13.48 (95% CI, 8.66%-18.31%).

Marcela Baraúna MAGNO (a) Aline Borburema NEVES (a) Raildo da Silva COQUEIRO (b) Marcelo de Castro COSTA (a) Lucianne Cople MAIA (a) Matheus Melo PITHON (a)

The aim of this study was investigate`s patient and parent’s aesthetic perception and psychological impact of molar-incisor hypomineralisation (MIH) and to assess the correlation of MIH with caries experience. The sample comprised 56 children, 28 with MIH and 28 without MIH (comparison group), and their gardens (n=56). For the perception data we used the Child and Parent’s Questionnaire of Teeth Appearance. We used the European Academic of Paediatric Dentistry (EAPD) criteria to define MIH. Caries experience was assessed by Decayed, Missing and Filled Teeth (DMFT) index. Chi-square, Student’s t-test and correlation tests were used with significance level set at 5%. Most children were male (n=35; 62.5%) and patients with MIH perceived their affected teeth as stainned (p=0.01). MIH was considered by parents (6.96±1.7) to enhance psychosocial condition (social, physical, and psychological social) of their children (p<0.01). Patients with severe MIH showed the worst perception about the color of the teeth (p=0.07). There was no correlation between DMFT scores and presence of MIH (p=0.80). Patients and parents perceived MIH. Groups with severe MIH (children/ parents) showed the worse aesthetic perception.

BackgroundMolar hypomineralization (MH) is defined as a multifactorial condition, and thus, its presence may be defined by interactions between environmental and genetic factors.AimTo evaluate the association between MH, genes involved in enamel development, and the use of medication during pregnancy in early childhood.DesignOne hundred and eighteen children, 54 with and 64 without MH, were studied. The data collected included demographics, socioeconomic data, and the medical history of mothers and children. Genomic DNA was collected from saliva. Genetic polymorphisms in ameloblastin (AMBN; rs4694075), enamelin (ENAM; rs3796704, rs7664896), and kallikrein (KLK4; rs2235091) were evaluated. These genes were analyzed by real‐time polymerase chain reaction using TaqMan chemistry. The software PLINK was used to compare allele and genotype distributions of the groups and to assess the interaction between environmental variables and genotypes (p < .05).ResultsThe variant allele KLK4 rs2235091 was associated with MH in some children (odds ratio [OR]: 3.75; 95% confidence interval [CI] = 1.65–7.81; p = .001). Taking medications in the first 4 years of life was also associated with MH (OR: 2.94; 95% CI = 1.02–6.04; p = .041) and specifically in association with polymorphisms in ENAM, AMBN, and KLK4 (p < .05). The use of medications during pregnancy was not associated with MH (OR: 1.37; 95% CI = 0.593–3.18; p = .458).ConclusionThe results of this study suggest that taking medication in the postnatal period appears to contribute to the etiology of MH in some evaluated children. There may be a possible genetic influence of polymorphisms in the KLK4 gene with this condition.

Radicular cysts are considered rare in primary dentition. The aim of this article was to present two cases of radicular cysts associated to primary molars with different characteristics. Two children sought care at a dental clinic with complaints of a painless swelling and the absence of a premolar, respectively. The first case was a seven-year-old boy who complained of an increased volume in the region of the mandibular right primary second molar. The second case was a 12-year-old girl, who complained of the absence of the mandibular right second premolar and gingival inflammation. In both cases, surgery was performed to remove the lesion and the elements involved. Histological examinations confirmed the radicular cysts. After six months, complete regression of the lesions was reported, and the patients were referred for orthodontic treatment. Radicular cysts can cause damage to the elements involved, adjacent teeth and the occlusion of the patient.