Funding. The "Acti-GPS" project was promoted by the University Hospital of Angers and was partially funded by the Genesia Foundation. The "CLASH" project was promoted and partially funded by the University Hospital of Rennes (CORECT 2013). Both the "Acti-GPS" and "CLASH" projects were also partially funded by ENS Rennes. A. Taoum received a postdoctoral scholarship from the ENS Rennes and the Bretagne region (SAD funding). S. Chaudru received a PhD scholarship from the Bretagne region (ARED funding). P.-Y. de Müllenheim received a PhD scholarship from the ENS Cachan-Antenne de Bretagne (CDSN). Conflicts of Interest. None. The results of the present study do not constitute endorsement by ACSM. The results of the study are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation.

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We aimed at showing how Global Positioning System (GPS) along with a previously validated speed processing methodology could be used to measure outdoor walking capacities in people with multiple sclerosis (MS). We also deal with methodological issues that may occur when conducting such measurements, and explore to what extent GPS-measured outdoor walking capacities (maximal walking distance [MWDGPS] and usual walking speed) could be related to traditional functional outcomes (6-min total walking distance) in people with MS. Eighteen people with MS, with an Expanded Disability Status Scale score ≤6, completed a 6-min walking test and an outdoor walking session (60 min maximum) at usual pace during which participants were wearing a DG100 GPS receiver and could perform several walking bouts. Among the 12 participants with valid data (i.e., who correctly completed the outdoor session with no spurious GPS signals that could prevent the detection of the occurrence of a walking/stopping bout), the median (90% confidence interval, CI) outdoor walking speed was 2.52 km/h (2.17; 2.93). Ten participants (83% (56; 97)) had ≥1 stop during the session. Among these participants, the median of MWDGPS was 410 m (226; 1350), and 40% (15; 70) did not reach their MWDGPS during the first walking bout. Spearman correlations of MWDGPS and walking speed with 6-min total walking distance were, respectively, 0.19 (−0.41; 0.95) and 0.66 (0.30; 1.00). Further work is required to provide guidance about GPS assessment in people with MS.

The self-completion of CDQ2 compared to FFQ was associated with far less errors. There was a significant correlation between CDQ2 and FFQ. Preference should be given to CDQ2 in clinical practice and in studies where dietary pattern are evaluated without any interviewer.