Our study aimed to create a machine learning model to predict patients’ functional outcomes after microsurgical treatment of unruptured intracranial aneurysms (UIA). Data on 615 microsurgically treated patients with UIA were collected retrospectively from the Electronic Health Records at N.N. Burdenko Neurosurgery Center (Moscow, Russia). The dichotomized modified Rankin Scale (mRS) at the discharge was used as a target variable. Several machine learning models were utilized: a random forest upon decision trees (RF), logistic regression (LR), support vector machine (SVM). The best result with F1-score metric = 0.904 was produced by the SVM model with a label-encode method. The predictive modeling based on machine learning might be promising as a decision support tool in intracranial aneurysm surgery.
The study objective is to report a case of dynamic neuropathy of the common peroneal nerve at the level of the fibular head and to discuss diagnostic methods and neurosurgical treatment. Materials and methods. We report a case of dynamic neuropathy of the common peroneal nerve at the level of the fibular head in a female patient. The patient was treated in the Neurology Clinic of I.M. Sechenov First Moscow State Medical University. We analyzed clinical manifestations and compared them with the data described in research literature. Results. Upon admission, the patient complained of pain in the anterolateral surface of the right shin and in the dorsum of the foot during walking. At rest, the patient experienced no pain. We observed no motor or sensory disorders typical of nerve root disorders at the level of L5. Lasegue’s test was negative. The patient had a positive Tinel’s sign in the area of the right fibular head. In order to clarify the diagnosis, we performed a repeated extension test in the right ankle joint and it was positive. The patient underwent surgery that included peroneal nerve decompression and neurolysis at the level of the fibular head. In the postoperative period, the patient had complete pain relief. Conclusion. Due to the difficulties in the diagnostics of dynamic neuropathy of the common peroneal nerve, this disease is often mistaken for radiculopathy at the level of L5. Thorough clinical examination, testing for Tinel’s sign in the area of the fibular head, and repeated extension test in the ankle joint ensure the correct diagnosis and reduce the frequency of ineffective surgeries on the lumbar spine. Surgical decompression of the common peroneal nerve at the level of the fibular head with obligatory opening of the entrance to the nerve canal is an effective method of treatment in such patients.
Представлено описание пациентки с нейрокожным меланозом (НКМ) в сочетании с аномалией Денди-Уокера и спинальной арахноидальной кистой, находившейся на лечении в Клинике нервных болезней им. А.Я. Кожевникова. В течение года у больной нарастала неврологическая симптоматика в виде центрального нижнего парапареза и координаторных расстройств, консервативное лечение было неэффективно. При нейровизуализации выявлены аномалия Денди-Уокера и спинальная арахноидальная киста. Проведено хирургическое вмешательство-фенестрация верхнего и нижнего полюсов арахноидальной кисты на уровне СVI-VII и ТIX-X. В cвязи с отсутствием клинического результата через 1 мес выполнена повторная операция-иссечение спайки в полости арахноидальной кисты на уровне ТV-VI; имплантация кистоперитонеального шунта. После операции отмечен регресс неврологических расстройств. Описанный клинический случай является уникальным, поскольку НКМ-крайне редкая патология, особенно при сочетании аномалии Денди-Уокера и арахноидальной кисты. Помимо этого, представляет интерес то, что манифестация неврологических симптомов и верификация диагноза произошли уже во взрослом возрасте, хотя наиболее часто НКМ диагностируется у детей. Настоящее наблюдение показывает, что операция, направленная на улучшение ликвородинамики у пациентов с арахноидальными кистами и комплексом Денди-Уокера на фоне НКМ, может приводить к значительному регрессу неврологической симптоматики и улучшению качества жизни, несмотря на грубые структурные изменения мозга, выявляемые при магнитно-резонансной томографии.
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