Toxoplasmosis is a common, mainly asymptomatic infection in warm-blooded mammals and bird^.^.^ The infection appears to be more common in some animal species than in others, and there are relatively few reports involving marine mammals. Among marine mammals, toxoplasmosis has been reported in several pinnipeds2 and a manatee' but not in cetaceans. A recent infection involving a female Atlantic bottle-nosed dolphin (Tursiops truncatus) and her calf found beached in Florida is on file at the Armed Forces Institute of Pathology.6We report toxoplasmosis in a wild, free-living male spinner dolphin (Stenella longirostris). The animal was 199 cm long and was found beached on Chun's Reef, Haleiwa, Oahu, Hawaii. The carcass was thin, dehydrated, and had very little ingesta in the stomach, and the intestine was empty. Numerous ulcers were noted on the gums, tongue, and oral mucosa. Unidentified tapeworm cysts were found in the skeletal muscle. Consolidation was present in the anterior portion of the left lung, and numerous small nodules were scattered throughout the liver.Although not all of the organs were available for histologic examination, the adrenal glands were severely affected, with numerous large, discrete areas of coagulative necrosis in the cortex (Fig.1). Fewer lesions were in the medulla. Mononuclear leukocytic aggregates composed of lymphocytes and macrophages were found at the periphery of the necrotic areas. In the parenchymal cells were numerous organisms of Toxoplasma gondii, including both tachyzoites (Fig. 2) and tissue cysts. The bradyzoites in tissue cysts stained positively with the periodic acid-Schiff technique (Fig. 3). A diffuse encephalitis was present with numerous small foci of gliosis associated with tissue cysts. The liver had many small, randomly distributed, necrotic foci containing mononuclear leukocytic infiltrates, and T. gondii organisms were found occasionally in hepatocytes. The testes had several small necrotic foci, but no T. gondii was seen. A severe subacute to chronic
A Leptospira species is suspected of being the etiological agent in a recent epizootic among California sea lions. The disease was confined to subadult males of the species
Zalophus c. californianus
.
Lesions of candidiasis, mucormycosis (phycomycosis), entomophthoramycosis, geotrichosis, cryptococcosis, paracoccidioidomycosis and coccidioidomycosis have been reported in the alimentary tract of nonhuman primates. Candidiasis and mucormycosis were reported most often. Both Old and New World monkeys and great apes are susceptible; infection is rare in prosimians. Ulcers and necrosis of the mucosa of the alimentary tract are the principal gross lesions. A granulomatous inflammatory process occurs in which the fungi are visible histologically on hematoxylin and eosin (HE)-stained sections, but they are seen and characterized better when stained with periodic acid-Schiff (PAS) or Gomori methenamine silver (GMS) techniques. Cultural or immunofluorescence studies, or both, are necessary for specific identification of the fungi. Immunosuppression is suggested as a predisposing factor in certain mycotic diseases.
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