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I Inactive or nonfunctional ovaries are one of the most important reported causes of the prolonged postpartum anestrum that resulted to the delayed onset of estrus and inefficient breeding in buffaloes. The suggested study of progesterone in the blood serum of buffalo could be potentially useful as far as the hormone content that might reflect the postpartum condition in the buffalo-cows. This study aimed to evaluate the effect of exogenous progesterone in treatment of ovarian inactivity in the Egyptian dairy parturient buffalo-cows. This study was carried out on parturient buffalo-cows came to veterinary clinic and owned by small holders. These buffalo-cows ages ranged between 2-5 years. The animals were divided into 4 groups (28 animals). First group (7 buffalo-cows) as control group without any treatment. The second group (5 buffalo-cows) to study the effect of Progesterone (prontogest®) + PGf2α treatment trial. Third group (7 buffalo-cows) to study the effect of CIDR treatment trail. Forth group (9 buffalo-cows) to study the effect of CIDR+GPG protocol as a treatment trail. Progesterone level was measured before treatment (for diagnosis) and after treatment (to detect the response of treatment). The results indicated that using CIDR+GPG gave good results for the treatment of ovarian inactivity in buffalo-cows, where increased the incidence of estrus and improved the reproductive parameters in dairy parturient buffalo-cows.

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