We report the largest scale MS based proteome of human fallopian tube (hFT). Ribosome, cytoskeleton, and vesicle associated proteins showed high abundance in hFT. Extraordinary high coverage of MSCs associated proteins in the hFT proteome.
We present observations of 12C32S, 12C34S, 13C32S, and 12C33S J = 2−1 lines toward a large sample of massive star-forming regions by using the Arizona Radio Observatory 12 m telescope and the IRAM 30 m. Taking new measurements of the carbon 12C/13C ratio, the 32S/34S isotope ratio was determined from the integrated 13C32S/12C34S line intensity ratios for our sample. Our analysis shows a 32S/34S gradient from the inner Galaxy out to a galactocentric distance of 12 kpc. An unweighted least-squares fit to our data yields 32S/34S = (1.56 ± 0.17)D
GC + (6.75 ± 1.22) with a correlation coefficient of 0.77. Errors represent 1σ standard deviations. Testing this result by (a) excluding the Galactic center region, (b) excluding all sources with C34S opacities >0.25, (c) combining our data and old data from previous study, and (d) using different sets of carbon isotope ratios leads to the conclusion that the observed 32S/34S gradient is not an artifact but persists irrespective of the choice of sample and carbon isotope data. A gradient with rising 32S/34S values as a function of galactocentric radius implies that the solar system ratio should be larger than that of the local interstellar medium. With the new carbon isotope ratios, we indeed obtain a local 32S/34S isotope ratio about 10% below the solar system one, as expected in the case of decreasing 32S/34S ratios with time and increased amounts of stellar processing. However, taking older carbon isotope ratios based on a lesser amount of data, such a decrease is not seen. No systematic variation of 34S/33S ratios along galactocentric distance was found. The average value is 5.9 ± 1.5, the error denoting the standard deviation of an individual measurement.
BackgroundDespite increasing numbers of RCTs done in China, detailed information on the quality of Chinese RCTs is still missing. The aim of this study was to assess the reporting quality of RSA RCTs and to identify significant predictors of reporting quality.MethodsA literature review was conducted with the aim of identifying published RCTs on RSA conducted in China. In order to rate the report quality, we scored 1 for the item of CONSORT 2010 if it was reported and 0 if it was not stated or unclear. An overall quality score (OQS) with a range of 0–15 and a key methodological index score (MIS) with a range of 0–3 were calculated for each trial.ResultsA total of 98 relevant RCTs were included in the final analysis. The median OQS was 7, with a minimum of 1 and maximum of 12. The general level of OQS was not high, especially among ‘sample size,’ ‘baseline data,’ ‘outcomes and estimation,’ and ‘ancillary analyses,’ all of which had a positive rate of less than 10%. The median MIS was 1 with a minimum of 0 and maximum of 1. ‘Allocation concealment,’ ‘blinding,’ and ‘intention-to-treat analysis’ were mentioned in 1 (1%), 1 (1%) and 69 (70%) of the studies, respectively. In univariate analysis, funding was the only factor associated with an increased OQS. Specifically, the mean OQS increased by approximately 1.52 for manuscripts supported by funding (95% CI: 0.12 – 2.92; p = 0.03). With regard to the MIS, no association was found for any variable.ConclusionRCTs of RSA conducted in China need improvement in order to meet the level of “reporting quality” required by the CONSORT statement.Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-015-0665-6) contains supplementary material, which is available to authorized users.
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