In our study of the substances involved in yeast growth stimulation carried out through a period of years, we first investigated extensively the nutrilite requirements of yeast number 578 (2331) of the American Type Culture Collection, and found that several unknown components must be present in order to stimulate its growth1,2'3 one of which may be the antineuritic vitamin4 of Jansen and Donath.Preliminary studies had been made upon a number of yeasts5 and we attempted to find other "strains" of Saccharomyces Cerevisiae which might have simpler requirements. The original strain used by Wildiers in his discovery of "bios" was investigated and the hypothetical "bios" was found beyond question to consist of two substances which were separable by fractional electrolysis, one an acid substance and the other basic.6Our work is now centered upon the requirements of the "Gebriide

No abstract

study has shown that the cleavage reaction between acid iodides and ethers proceeds in all probability through a preliminary formation of an oxonium compound between the ether and the acid iodide.Secondary ethers have been found to be much more readily cleaved into alkyl iodides and esters than are primary ethers. The substitution of chlorine in the «-position in aliphatic acid iodides has been found to diminish their ability to cleave ethers. The tendency of acetyl iodide, chloroacetyl iodide and dichloroacetyl iodide to split primary ethers was found to be diminished by increasing substitution of chlorine. Trichloroacetyl iodide showed no tendency to cleave either primary or secondary ethers at ordinary temperatures even in the presence of zinc iodide as a catalyst, though evidence of the formation of an oxonium compound was obtained. Similarly, substitution of chlorine in the «-position in aliphatic ethers greatly increased their resistance to cleavage by acid iodides.