The important research advances, in many scientific areas, have been fostered by an improvement of the computational strategies employed. As an example, High Performance Computing enables the collaborative usage of multiple processors to accelerate the resolution of scientific problems, and even to face large problems.However, there are several scientific applications whose computational requirements can exceed the computing capacities of a single organisation. This way, the recent advances in the bandwidth of the communication networks have leveraged the idea of joining geographically distributed resources, creating a global computing infrastructure known as the Grid.This thesis combines High Performance Computing and Grid Computing in order to accelerate the execution of scientific applications, and to allow solving problems that can not be solved, in a reasonable time, with the resources of a single organisation.For that purpose, a system that offers an abstraction layer to simplify the execution of general scientific applications, in Grid infrastructures, has been developed. This system, called GMarte, provides metascheduling functionality for the concurrent execution of parallel applications on resources based on the Globus Toolkit, the standard software in computational Grids. Later, and according to the current trend towards service-oriented architectures, a metascheduler Grid service has been created, featuring interoperability and based on standard technologies. This Grid service offers metascheduling functionality to multiple clients, which use high-level graphical applications to interact with it, using security mechanisms for data protection. This way, it is possible to simplify and foster the usage of Grid technologies for the efficient execution of scientific applications.The proposed computational approach has been applied to two biomedical applications: the cardiac electrical activity simulation and the protein design with targeted properties. First of all, a parallel simulation system of the action potential propagation on cardiac tissues has been developed.Secondly, an efficient system has been implemented for the design of proteins. In both cases, the usage of High Performance Computing has enabled to accelerate the executions as well as to face larger dimension problems.Finally, executions of both applications have been performed over different Grid deployments, in order to evaluate the advantages of a strategy that combines both computationally advanced techniques. 3 Títol Computació d'Altes Prestacions en Entorns Grid en Aplicacions Biomèdiques: Simulació de l'Activitat Elèctrica Cardiaca i Disseny de Proteines ResumEls importants avanços en la investigació, de nombrosesàrees de coneixement, han vingut propiciats per una millora en les estratègies de computació emprades. A mode d'exemple, la Computació d'Altes Prestacions permet la utilització col·laborativa de múltiples processadors per a accelerar la resolució de problemes científics, i fins i tot abordar problemes de major dimens...

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In this article, we describe a Java-based virtual laboratory, accessible via the Internet by means of a Web browser. This remote laboratory enables the students to build both direct and alternating current circuits. The program includes a graphical user interface which resembles the connection board, and also the electrical components and tools that are used in a real laboratory to build electrical circuits. Emphasis has been placed on designing access patterns to the virtual tools as if they were real ones. The virtual laboratory developed in this study allows the lecturer to adapt the behaviour and the principal layout of the different practical sessions during a course. This flexibility enables the tool to guide the student during each practical lesson, thus enhancing self-motivation. This study is an application of new technologies for active learning methodologies, in order to increase both the self-learning and comprehension of the students. This virtual laboratory is currently accessible at http://personales.upv.es/jogomez/labvir/ (in Spanish).

In this article, we describe a Java-based virtual laboratory, accessible via the Internet by means of a Web browser. This remote laboratory enables the students to build both direct and alternating current circuits. The program includes a graphical user interface which resembles the connection board, and also the electrical components and tools that are used in a real laboratory to build electrical circuits. Emphasis has been placed on designing access patterns to the virtual tools as if they were real ones. The virtuallaboratory developed in this study allows the lecturer to adapt the behaviour and the principal layout of the different practical sessions during a course. This flexibility enables the tool to guide the student during each practical lesson, thus enhancing self-motivation. This study is an application of new technologies for active learning methodologies, in order to increase both the self-learning and comprehension of the students. This virtual laboratoryis currently accessible at http://personales.upv.es/jogomez/labvir/ (in Spanish).

Este artículo recopila una serie de experiencias de analíticas de aprendizaje realizadas en un contexto universitario multi-disciplinar para poder facilitar el seguimiento del alcance de ciertas competencias transversales por parte del alumnado. Las experiencias involucran el uso de herramientas informáticas para la recopilación, análisis y/o procesado de datos generados principalmente a partir de las interacciones del estudiante con los Sistemas de Gestión del Aprendizaje utilizados en la Universitat Politècnica de València (PoliformaT, basado en Sakai, Microsoft Teams y Videoapuntes). Los resultados indican que la integración de técnicas de analíticas de aprendizaje permite recopilar evidencias y arrojar visibilidad de forma parcialmente automatizada con el objetivo de dar soporte al proceso de seguimiento del grado de alcance de ciertas competencias transversales.