Objective: To evaluate the functional capacity and quality of life of children and adolescents during cancer treatment and post-treatment. Methods: Cross-sectional study of patients during cancer treatment and post-treatment, assessed by the 6-minute walk test (6MWT) and the Pediatric Quality of Life ™ questionnaire (cancer module). Results: Sixty-five patients, aged 11.2±3.5 years, mostly males (50.8%) and white (90.8%), with high incidence of hematological cancers (81.5%) participated in the study. The performance in the 6MWT was 23.1% inferior comparing the mean predicted and achieved (584.3±5 and 447.7±78.6 m, respectively). The percentage difference between the predicted and achieved 6MWT, and the different phases of cancer treatment were significantly different between patients in treatment (73.7±12.8) and post-treatment (84.5±9.1). When grouped by the different diagnoses, it was possible to observe that the distance covered by the patients with leukemia showed results closer to that predicted (80.7±11.7). Regarding the health-related quality of life questionnaire (HRQL), the child’s perception (78.0±14.56) was better than that reported by their parents (72.4±17.74). However, when we compared HRQL with the 6MWT, there was no association between them (p=0.597). Conclusions: Children and adolescents undergoing cancer treatment or post-treatment showed a 23% deficit in functional capacity. In relation to HRQL results, children’s perception was higher than that of their parents.

Objective/Background: Hematopoietic stem cell transplantation (HSCT) is a treatment for benign and malignant hematological diseases. These aggressive treatments cause reduced levels of physical activity, decreased lung function, and worse quality of life. Alterations in pulmonary function tests before HSCT are associated with the risk of respiratory failure and early mortality. The objective of this study was to evaluate functional capacity and lung function before and after HSCT and identify the predictors of mortality after 2 years. Methods: A prospective cohort study was carried out with individuals with oncohematological diseases. The evaluations were carried out in two moments during hospitalization and at hospital discharge. Follow-up was carried out after 48 months. Assessments were carried out on 34 adults, using spirometry, manovacuometry, 6-Minute Walk Test (6MWT), Handgrip Strength Test, and 30-Second Chair Stand Test (30-s CST). Results: There was a statistically significant reduction for the variables in forced vital capacity, forced expiratory volume predicted in the 1st second, Tiffeneau index, handgrip strength, and distance covered (% predicted) on the 6MWT (p < .05). There was a significant difference in the 30-s CST when individuals were compared according to the type of transplant. We found that a 10% reduction in the values of maximum inspiratory pressure (MIP) can predict an increased risk for mortality. Conclusions: Individuals undergoing HSCT have reduced functional capacity, lung function, and muscle strength during the hospitalization phase. Reduction in the values of MIP increases the risk of nonrelapse mortality.

Introdução: O câncer de mama é o que mais acomete as mulheres e pode trazer consequências funcionais. Objetivo: Avaliar os efeitos da mastectomia radical modificada sobre a propriocepção, sensibilidade e funcionalidade do membro homolateral a cirurgia e relacionar a sensibilidade com a propriocepção. Métodos: As avaliações foram no período pré-operatório e pós-operatório de 60 dias, utilizando-se o cinesiômetro, estesiômetro e o questionário Disabilities of the Arm, Shoulder and Hand (DASH). Resultados: Foram avaliadas 8 mulheres. Não houve diferença de funcionalidade no pré e pós-operatório (p = 0,156), na sensibilidade para os nervos torácico longo (p = 0,783) e intercostobraquial (p = 0,423), e propriocepção (p = 0,672). Houve correlação da sensibilidade nos dermátomos dos dois nervos com a propriocepção (r = 0,920 e r = 0,723). Conclusão: O tratamento do câncer não teve influência expressiva sobre a propriocepção, sensibilidade e funcionalidade, mas encontrou-se relação entre sensibilidade e propriocepção do membro superior.Palavras-chave: propriocepção, fisioterapia, mastectomia, neoplasias.

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