No abstract

Antiviral activities were enhanced by HCV core transduction, but they were not associated with the HCV core aa70 and/or aa91 substitutions by in vitro analysis.

The anti-ulcer agent teprenone inhibited HCV RNA replication and enhanced statins' inhibitory action against geranylgeranylation. This newly discovered function of teprenone may improve the treatment of HCV-associated liver diseases as an adjuvant to statins.

No abstract

A case of intracranial malignant teratoma found in a 27‐year‐old man was reported. This unique tumor was found in the right frontal lobe separated from the pineal region and revealed various tissue components such as stratified squamous epithelium, glandular tissues, neuron, glia, ependyma, fibro‐muscular tissue, cartilage, bone, hemangiomatous lesion, malanin‐laden cells, and some germ cell components. An immunohistochemical study demonstrated the presence of S‐100 protein, glial fibrillary acidic protein (GFAP), neuron‐specific enolase (NSE), carcinoembryonic antigen (CEA), and Factor VIII in some tumorous components. In particular, the distribution of S‐100 protein in some germ cells suggested the possibility of the neuroectodermal origin of the germ cells or, alternatively, differentiation to the neuroectoderm.