Objectives In view of the lack of studies about the morphological and structural changes caused by solar radiation in young people, the aim of the present study was to evaluate the photoageing‐related changes in the skin of different age groups by biophysical and imaging techniques. Methods Forty‐four healthy female subjects were divided into two age groups: Group 1 (G1): 18–35 years old and Group 2 (G2): 40–60 years old. The skin of malar region of the face was evaluated in terms of mechanical properties, disorder in the pigmentation pattern, morphological and structural changes using the Cutometer®, Colorimeter®, Visioface® and Dermascan C® devices and reflectance confocal microscopy (Vivascope®). Results The results showed that the main changes in the skin of G1 were related to the pigmentation pattern, the papilla format and depletion of thin collagen fibres. These alterations were also observed in the skin of G2, but with more pronounced effects. Conclusion The knowledge about the skin changes caused by photoageing obtained in this study is very important for the development of dermocosmetic products for more effective treatments particularly focused on this type of skin. Finally, objective characterization of photoageing showed the importance of photoprotective habits since the first years of life in order to retard the appearance of skin changes caused by solar radiation.

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Avaliação do efeito do licopeno no tecido ósseo da calvária de ratas ovariectomizadas: estudo in vitro em células osteoblásticas e in vivo com implante de scaffold de PLLA/licopeno em defeitos ósseos críticos. Ribeirão Preto 2021 GUILHERME ALVARENGA ALVES Avaliação do efeito do licopeno no tecido ósseo da calvária de ratas ovariectomizadas: estudo in vitro em células osteoblásticas e in vivo com implante de scaffold de PLLA/licopeno em defeitos ósseos críticos.