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We aimed to present the effectiveness of percutaneous transhepatic cholangiography, percutaneous biliary drainage and metallic endoprotesis applications in patients with inoperable biliary obstructions. Material and Method:Percutaneous transhepatic cholangiographies (PTC) and percutaneous biliary drainages (PBD) were performed in 44 patients with inoperable malignant obstructive jaundice who had been hospitalized in the radiology department of our hospital over a three years period. Six patients (13.6%) underwent external biliary drainage(EBD), 27 patients (61.4%) underwent internal-external biliary drainage(I-EBD) and metallic stents were placed in 11 patients (25%) on average 6 days (1-34 days) after I-EBD. The mean total bilirubin(TB), ALP, ALT, AST, GGT values taken before and after drainage in all patients were compared.Results: Biliary drainage was technically successful in all patients. In the first two weeks after biliary drainage, 38 cases (86%) had a general condition improvement, weakness and itching decreased.