Relief of pain was almost immediate, but twenty minutes later he was in a collapsed state, respiration was rapid, and marked bronchospasm was present. The face, lips, and tongue were swollen, and a generalized urticuria was apparent. Retrosternal and abdominal pain was present, and ho complained of discomfort in elbow, wrist, knees, and aikle-joints. On,2 millilitre of 1:1,000 adrenaline was slowly administered subcutaneously, and 10 mg. of chlorpheniramine maleate (" piriton ") was given intravenously, and a further 10 mg. intramuscularly. Recovery was slow; however, the major symptoms cleared after forty minutes. Severe urticarial itch persisted, but it was interesting to note that there was no local reaction at the site of the infiltration. He was given further " piriton " orally, 4 mg. q.i.d. Recovery was complete within 4 hours, and the pain due to the
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