No abstract

method of freezing did not have any detectable differential effect on Pyf density, % gH2AX+ Pyf or Pyf. CONCLUSIONS: Based on the impact on primordial follicle survival and DNA damage after thaw and culture, there seems to be no major differences between the SF and VF methods. It appears that fewer apoptotic follicles survive after VF but this does not have any impact on final non-apoptotic follicle density or survival in culture. This is the first comprehensive laboratory comparison of SF vs. VF in human ovarian tissue and it suggests that SF and VF may be interchangeable methods.

No abstract

No abstract

chi square where applicable. Multivariable logistic regression was performed to account for possible confounding.RESULTS: There was no significant difference in baseline AMH or antral follicle counts among groups (Table 1). Number of oocytes retrieved and blastocysts obtained were similar between groups. There was no significant difference in ongoing pregnancy rates. (72.6% and 69.1%).CONCLUSIONS: Extremes of oocyte donor age does not predict cycle outcomes. Donors age 21-23 at the time of oocyte donation produced comparable number of oocytes and blastocysts when compared with donors age 28-31. More importantly, the two groups had comparable clinical pregnancy rates and aneuploidy rates. Given the frequent request from donor oocyte recipients to use younger donors, the findings of this study are of practical clinical importance for patient counseling.