No abstract

Le déficit en cellules germinales est loin de suffire à expliquer, à lui seul, l'arrêt de croissance des gonades. Le

Le déficit en cellules germinales est loin de suffire à expliquer, à lui seul, l'arrêt de croissance des gonades. Le

Chromosomal analyses of several tissues of a bovine true hermaphrodite revealed a diploid XX/triploid XXY chimerism. This is believed to be the first report of an established triploid cell line in Bos taurus. Only XX diploid or near diploid cells were seen in the first 300 metaphases from cultured peripheral blood, but a single 88, XXY metaphase was found when an additional 400 metaphases were scored. Three diploid XXY cells, analogous to human Klinefelter cells, and 221 diploid or near diploid XX cells were seen in 224 bone-marrow metaphases. Only the diploid XX cell line was observed in 200 metaphases from a skin specimen. The triploid cell line would have gone undetected if only 200 metaphases per culture of blood, skin and bone marrow had been examined. This finding illustrates the ease with which chimerism can be overlooked in some extreme cases. The triploid cell line was present in the kidneys, right prefemoral lymph node, uterus and gonads. The incidence of triploid cells was significantly higher in mesodermal tissues of the right side homolateral to the ovotestis and significantly higher in the testicular portion of the ovotestis (P < 0.001).