This work was aimed to prepare new monomer (E)-1-(4-aminophenyl)-3-(4-hydroxyphenyl) prop-2-en-1-one] and three types of poly (ester-amide) polymers. New monomer is Chalcone compound α,βunsaturated ketone contain functional group(-CO-CH=CH-) of presence system α,βunsaturated carbonyl group. It is prepared by condensation aryl ketone with aromatic aldehyde with presence of suitable condensation agents which called Aldol condensation. Monomer reacted with (phthalic anhydride maleic anhydride salicylic acid and succinic anhydride) Via solution poly condensation reactions to yield three types of polymers. The prepared monmer and polymers were characterized by [(FT.IR-spectra, Nuclear magnetic resonance 1H.NMR-spectra , 13C.NMRspectra and Differential scanning calorimetry (DSC)] All the polymers showed good thermal stability and good data of glass transition temperature (Tg). The results revealed that poly (ester-amide)s were successfully prepared by giving good spectrum which improved the existed amide functional group (-CONH-) and ester functional group (-COO-) in spectrum of each prepared polymer, furthermore the existed chalcone functional group(-CO-CH=CH-) is improved in spectrums of monomer.

In the present work , 4-((dicyanomethyl)diazenyl)-N-(5-methylisoxazol-3-yl)benzene sulfonamide E and 2,2'-(1E,1E')-(sulfonylbis(4,1-phenylene))bis(diazene-2,1-diyl) dimalononitrile C were synthesized from the reaction of Sulfamethaxazole and Dapsone with Malononitrile and condensed with 2,4dinitophenyl hydrazine derivatives to produce 3,5diaminopyrazole derivatives E1 and C1.condensation with hydroxyl amine hydrochloride produce isoxazole derivative E2,C2 .Treatment of E and C with urea and thiourea yielded the pyrimidine derivatives E3-E4,C3-C4 and treatment with secondary amine afforded piperazine derivatives E5,C5. While its condensation with thiosemicarbazide yielded the derivatives E6, C6. The structure of the newly synthesized compound were established on the basis of physical data and spectral methods such as IR, 1H-NMR ,13C-NMR and Mass spectra. Cytotoic evaluation of four compounds, against MCF-7 (human breast adeno carcinoma) cell lines.

The Novel Heterocyclic ligands N-phenyl-4-{[(2,4,6-trioxotetrahydro pyrimidin-5(2H)ylidene)methyl]amino}benzene sulfonamide (L1) and 5-{[(3-hydroxy phenyl)amino]methylene}pyrimidine-2,4,6(1H,3H,5H)-trione (L2) were prepared to give the final poly dentate Heterocyclic with different donor atom system. All the synthesized ligands were characterized using 1H,13CNMR, Mass Spectra, C.H.N. microanalysis and studied by FTIR, UV.-Vis. techniques. with TLC technique for each steps of prepare reactions and melting points. New complexes of the general formulae [Pd (L1)2] and [Pd (L2)2], have been isolated. The complexes were characterized by elemental analyses, conductivity measurements, magnetic susceptibilities and spectroscopic (IR, 1H NMR and UV-Vis ) studies and melting points. All the data are discussed in terms of the nature of the bonding and the possible structural types. All preparation of complexes of Pd (II) ion were deduced according to the molar ratio (2:1) (L:M) depending on the Micro elemental Analysis (C.H.N.S). The Ligands behaves as a Didentate ligand in the monomeric complexes. According to the results obtained, Square Plainer structure suggested for the prepared complexes.

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