In the present paper, many unsaturated polyesters has been synthesized using maleic anhydride, phthalic anhydride and succinic anhydride for esterification with new monomer [E)-1-(4-hydroxyphenyl)-3-(3-methoxy-4-hydroxyphenyl) prop-2-en-1-one]. These polyesters were polymerized by condensation reaction . Their chemical structures were characterized using FTIR, 13C-NMR and 1H NMR spectroscopy. Thermal properties have been analysed using Differential Scanning Calorimetry of synthesized polyesters .All the polymers showed well thermal stability and perfect data of glass transition temperature (Tg) also the results showed polyesters and monomer were successfully synthesized by giving well spectrum improved existing an ester functional group (-COO-) in spectrums each polymer prepared also existent Chalcone functional group(-CO-CH=CH-) in spectrum of monomer.

This work was aimed to prepare new monomer (E)-1-(4-aminophenyl)-3-(4-hydroxyphenyl) prop-2-en-1-one] and three types of poly (ester-amide) polymers. New monomer is Chalcone compound α,βunsaturated ketone contain functional group(-CO-CH=CH-) of presence system α,βunsaturated carbonyl group. It is prepared by condensation aryl ketone with aromatic aldehyde with presence of suitable condensation agents which called Aldol condensation. Monomer reacted with (phthalic anhydride maleic anhydride salicylic acid and succinic anhydride) Via solution poly condensation reactions to yield three types of polymers. The prepared monmer and polymers were characterized by [(FT.IR-spectra, Nuclear magnetic resonance 1H.NMR-spectra , 13C.NMRspectra and Differential scanning calorimetry (DSC)] All the polymers showed good thermal stability and good data of glass transition temperature (Tg). The results revealed that poly (ester-amide)s were successfully prepared by giving good spectrum which improved the existed amide functional group (-CONH-) and ester functional group (-COO-) in spectrum of each prepared polymer, furthermore the existed chalcone functional group(-CO-CH=CH-) is improved in spectrums of monomer.

The Novel Heterocyclic ligands N-phenyl-4-{[(2,4,6-trioxotetrahydro pyrimidin-5(2H)ylidene)methyl]amino}benzene sulfonamide (L1) and 5-{[(3-hydroxy phenyl)amino]methylene}pyrimidine-2,4,6(1H,3H,5H)-trione (L2) were prepared to give the final poly dentate Heterocyclic with different donor atom system. All the synthesized ligands were characterized using 1H,13CNMR, Mass Spectra, C.H.N. microanalysis and studied by FTIR, UV.-Vis. techniques. with TLC technique for each steps of prepare reactions and melting points. New complexes of the general formulae [Pd (L1)2] and [Pd (L2)2], have been isolated. The complexes were characterized by elemental analyses, conductivity measurements, magnetic susceptibilities and spectroscopic (IR, 1H NMR and UV-Vis ) studies and melting points. All the data are discussed in terms of the nature of the bonding and the possible structural types. All preparation of complexes of Pd (II) ion were deduced according to the molar ratio (2:1) (L:M) depending on the Micro elemental Analysis (C.H.N.S). The Ligands behaves as a Didentate ligand in the monomeric complexes. According to the results obtained, Square Plainer structure suggested for the prepared complexes.

A series of four- membered rings has been synthesized from Dapsone drug. In the first step examination Dapsone has been taken as initial material and treated with 4-aminoacetophenone to prepare new Azo compound. then Azo compound reacts with various aromatic amines in absolute ethanol to prepare Schiff bases derivatives. In the second step these derivatives react with Chloroacetylchloride in the presence of tri ethyl amine(Et3N) to prepare new four- membered heterocyclic compounds . All these derivatives were tested against different bacteria(Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus anthracis). The high efficacy results of these derivatives proved significantly greater than the efficacy of the same Dapsone drug.These compounds were identified and confirmed by FT- IR, 1HNMRand 13C-NMR.

This paper involves synthesis new Mannich bases derived from Shiff' bases which prepared from isatin by the reaction of isatin with different aromatic amines to prepare Shiff bases derivatives (M, G, B, R, X, S), then Shiff's bases derivatives reacted with formaldehyde and piperazine to produce Mannich bases derivatives (M1, G1, B1, R1, X1, S1). The third step included the assay of biological activity of all compounds against four types of pathogens bacteria (Staphylococcus aureus, Granutice tella adiacens) gram positive and (E. coli, Proteus mirabilis) gram negative the results exhibited excellent biological activity for all derivatives compared to antibiotics (Ampicillin and Ciprofloxacin) these structures were identified by FT-IR,1HNMRand 13CNMR.