PEMF combine with chitosan grafting could be considered as an effective, safe and tolerable treatment for peripheral nerve repair in clinical practice.
The aim of the current study was to determine effect of a nanocomposite containing ostrich eggshell (NCOE) on the calvarium healing in the rabbit. Fresh ostrich eggshell was ground (300-500 μm), treated in phosphate-containing solutions and sterilized by gamma irradiation. Fifteen New Zealand white adult male rabbits were used. Four full-thickness skull defects were created in the calvarium. The first defect kept unfilled (control). The second defect was filled with autograft bone. The third defect was filled using NCOE. The fourth defect was filled with mixture of the autograft+NCOE bone. At 30, 60 and 90 days after surgery animals were euthanized and tissue specimens were collected and stained with hematoxylin eosin and trichrome staining method. Microsections were examined toassess the extent and intensity of inflammation, calvarium formation status and foreign body reaction. According to the results, filling defect significantly increased in NCOE-treated rabbits compared to the control group at 30 and 60 days post-surgery (P<0.05). There a statistically significant difference between experimental groups compared to the control group at 30 and 60 days post-surgery (P<0.05) while no statistically significant differences were observed among autograft, NCOE, autograft+NCOE (P>0.05). Also, absorb material significantly decreased in NCOE and autograft+NCOE groups compared to the control group at 60 days post-surgery (P<0.05). The filling defect significantly increased in autograft, NCOE and NCOE+autograft groups compared to the control group at 90 days post-surgery (P<0.05). There was no significant difference on inflammation and absorb material among the groups at 90 days post-surgery (P>0.05). These results suggested NCOE+autograft has improved the rate of calvarium healing in rabbits.
Fractures of the mandible and maxilla are common in horses. The present study was conducted on fifteen horses referred for the management of mandible or maxilla fractures. Fixation methods were used to repair the fractures in these horses, including tension band and cerclage wires, dynamic compression plates, and lag screw fixation. All procedures were performed under chemical restraint and regional nerve block anesthesia in the standing position. According to the results, the long term follow-up of the horses was satisfactory, and no severe complications were observed. Jaw fractures are most successfully treated by early diagnosis and fracture fixation. The surgical management of most oral region injuries may be readily performed in the standing position, to avoid the risks associated with general anesthesia in horses.
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