Penyakit Diabetes Melitus  jumlahnya terus meningkat serta menjadi masalah kesehatan karena komplikasinya, terjadi akibat kurangnya pengetahuan maupun sikap Keluarga dalam kontrol gula darah. Tujuan penelitian ini adalah untuk menganalisis hubungan pengetahuan dan sikap keluarga dengan terkendalinya kadar gula darah pada pasien DM tipe-2. Rancangan penelitian analitik dengan pendekatan cross sectional. Sampel 46 Responden keluarga (extended) pasien diambil dengan accidental sampling. Dilaksanakan di RSUD Kabupaten Kediri Bulan Februari sampai Maret 2016. Variabel bebas pengetahuan skor 0-30 dan sikap skor 0-120 tentang terkendalinya kadar gula darah dengan lembar kuesioner, variabel terikat Terkendalinya kadar gula darah Glycohemoglobin (HbA1c) dalam % dengan lembar observasi Rekam Medis (HbA1c). Data  dinyatakan dalam skala interval dan di analisis menggunakan Regresi Linier berganda. Tingkat kesalahan (α) 5% (0,05). Hubungan pengetahuan keluarga dengan terkendalinya kadar gula darah (b= –0.29; CI 95%= -0.53 s/d -0.05; p=0.017 (30,1%)). Hubungan sikap keluarga dengan terkendalinya kadar gula darah (b= -0.125; CI 95%= -0.22 s/d -0.03; p=0,012 (31,1%)). Hubungan pengetahuan dan sikap keluarga dengan terkendalinya kadar gula darah p=0,001 (37%) terkendalinya kadar gula darah pada pasien Diabetes Melitus tipe-2 dipengaruhi oleh faktor pengetahuan dan sikap. Ada hubungan pengetahuan dan sikap keluarga dengan terkendalinya kadar gula darah pada pasien diabetes mellitus tipe-2.Kata Kunci : Pengetahuan Keluarga, Sikap Keluarga, Terkendalinya kadar gula darah

<p><strong>Pendahuluan</strong>: Kanker payudara merupakan keganasan pada wanita yang memiliki prosentasi dan angka mortalitas cukup tinggi baik di dunia maupun Indonesia. Pada kanker payudara memiliki reseptor untuk hormon estrogen, progesteron, dan protein Her–2 yang berperan dalam proses terjadinya sel kanker. Dimana keberadaan ER, PR dan Her-2/Neu serta Grading Histopatologi sangat mempengaruhi manajemen dan prognosis pada pasien dengan karsinoma payudara.</p><p><strong>Tujuan:</strong> Mengetahui hubungan antara Reseptor Estrogen, Reseptor Progesteron dan ekspresi Her-2/neu dengan grading histopatologi pada penderita wanita dengan kanker payudara.</p><p><strong>Bahan &amp; Metode:</strong> Pasien kanker payudara sejumlah 73 orang yang berobat di Poliklinik dan dirawat di bangsal serta pengambilan sample di sub Bagian Bedah Onkologi RSUD dr. Moewardi Surakarta antara April sd Desember 2018. Pemeriksaan Immunohistokimia dan Histopatologi di bagian Patologi Anatomi RSUD dr. Moewardi Surakarta. Penelitian prospektif analitik korelasi dengan cross sectional.</p><p><strong>Kesimpulan:</strong> Tidak terdapat hubungan antara reseptor estrogen dengan grading histopatologi pada pasien kanker payudara di RSUD dr. Moewardi Surakarta Jawa Tengah (p=0,901).Tidak terdapat hubungan antara reseptor progesteron dengan grading histopatologi pada pasien kanker payudara di RSUD dr. Moewardi Surakarta Jawa Tengah ( p=0,512).Tidak terdapat hubungan antara ekspresi Her-2/neu dengan grading Histopatologi pada pasien kanker payudara di RSUD dr. Moewardi Surakarta Jawa Tengah ( p=0,629).</p><p> </p><p>Introduction: Breast cancer is a malignancy in women who have a high percentage and mortality rate both in the world and Indonesia. Breast cancer has receptors for the hormones estrogen, progesterone, and Her-2 protein which play a role in the process of cancer cells. Where the existence of ER, PR and Her-2 / Neu and Histopathology Grading greatly affect the management and prognosis in patients with breast carcinoma.</p><p>Objective: To determine the relationship between Estrogen Receptor, Progesterone Receptor and Her-2 / neu expression with histopathological grading in women with breast cancer.</p><p>Material &amp; Methods: There were 73 breast cancer patients who were treated at the Polyclinic and treated in the ward and taking samples in the sub-section of Surgical Oncology Hospital Dr. Moewardi Surakarta between April to December 2018. Immunohistochemistry and Histopathology Examination in the Anatomy Pathology section of RSUD dr. Moewardi Surakarta. Prospective analytic correlation research with cross sectional study.</p><p>Conclusion: There is no relationship between estrogen receptors with histopathological grade in breast cancer patients at dr. Moewardi Surakarta, Central Java (p = 0,901). There was no relationship between progesterone receptors and histopathological grade in breast cancer patients at dr. Moewardi Surakarta, Central Java (p = 0.512). There was no relationship between Her-2 / neu expression and histopathological grading in breast cancer patients at dr. Moewardi Surakarta, Central Java (p = 0.629)</p>

Pendahuluan: Setiap tahun, angka terjadinya kecelakaan lalu lintas selalu mengalami peningkatan seiring dengan peningkatan tingkat mobilisasi. Penelitian ini bertujuan untuk mengetahui ciri-ciri luka pada korban mati akibat kecelakaan lalu lintas yang ditangani Instalasi Forensik RSUD Dr. Moewardi Surakarta. Metode: Penelitian ini menggunakan metode deskriptif observasional dari data Visum et Repertum di RSUD Dr. Moewardi Surakarta. Teknik sampling pada penelitian ini adalah total sampling yaitu seluruh Visum et Repertum sejak Januari 2016  - Desember 2020. Hasil: Dari data Visum et Repertum pada tahun 2016 – 2020 didapatkan sebanyak 99 kasus forensik patologi kecelakaan lalu lintas dengan ciri-ciri luka sebagai berikut: (1) Lokasi luka yang paling banyak ditemukan yaitu di kepala dan ekstremitas bawah dengan jumlah yang sama masing-masing sebanyak 89,89%; (2) Jenis luka yang paling sering ditemukan adalah jenis luka terbuka sebanyak 94,94%; (3) Dasar luka paling banyak yaitu dasar luka tulang sebanyak 43,43%; (4) Tepi luka rata didapatkan sebanyak 6,06% dan tepi luka tidak rata sebanyak 14,14%; (5) Adanya patah tulang didapatkan sebanyak 41,41%. Kesimpulan: Lokasi luka paling banyak terdapat di kepala dan ekstremitas bawah, jenis luka yang paling sering ditemukan adalah luka terbuka, dasar luka paling banyak adalah dasar luka tulang, tepi luka paling banyak adalah tepi luka tidak rata, dan lebih banyak kasus yang tidak terdapat adanya penjelasan mengenai patah tulang.

Background: Cancer diagnosis and therapy that causes chronic stress, its progression to depression  increase cortisol and VEGF-c levels in advanced cervical cancer patientsObjective: To  know the VEGF-c, cortisol and HADS level  in advanced stage cervical cancer patients who get Psychocurative intervention Method : An experimental study of pretest – posttest controle group design in outpatient oncology clinic and ward of Doctor Moewardi General Hospital. Thirty subjects with advanced cervical cancer were randomly divided into 15 patients in the intervention group, and 15 in control. Psycho-curative intervention 4 times a month, 1 time a week, 60 minutes duration. Before and after intervention, each subject of the two groups was examined levels of VEGF-c, cortisol and HADS scores. Data obtained were analyzed by independent t test, Mann Whitney, Pair t and Wilcoxon with the 19th version of SPSS for Windows.Result and Discussion: Average VEGF-c levels before intervention 9006.53 ± 2181.49, after intervention 5631.20 ± 2071.55, p <0.001. The mean cortisol level before intervention was 12.29 ± 4.36, after intervention 6.71 ± 3.88, p <0.001. The mean HADS Anxiety score before intervention was 14.13 ± 3.02, after intervention 8.47 ± 3.07, p <0.001. Mean Depression HADS scores before intervention 13.80 ± 3.21, after intervention 7.20 ± 2.70, p <0.001.Conclusion : VEGF-c levels, cortisol, HADS anxiety scores and depression in patients with advanced cervical cancer decline after psychocurative intervention. Keywords : Psychocurative; VEGF-c; Cortisol; HADS; Cervical cancer

Background: Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by dengue virus. Until now, Dengue virus infection remains a health problem in Indonesia. The things which cause problems in DHF case are high mortality rates, diseases spread which areeasily spread, especially affect children. Handling of DHF patients need long of length of stay which has large costs. Subjects and Method: This was an analytic observational study with cross-sectional design.This study was conducted atDr. Moewardi Hospital, Surakarta, based on medical records. 32 samples were selected using purposive sampling. The independent variables were age, sex, platelet count, hematocrit value, and number of leukocytes. The dependent variable was length of stay. The data were obtained from medical records using Chi square test. Bivariate analysis was used to determine the factors which affected DHF on length of stay using Chi square, Kolmogorov Smirnov, continuing with multiple linear regression analysis. Results: The age of DHF patients was from 1 year of age to 53 years of age with an average age of 20.07 +13.45 years. The number of female patients was 15 patients. Platelets level (x 1,000) was 25 for minimum and 308 for maximum. Mean ± SD platelet was 94.86 + 67.97. Hematocrit level was 28 for minimum and 54 for maximum. Mean ± SD hematocrit was 40.69 + 6.59. Leukocytes level (x 1,000) was 1.6 for minimum and 10.8 for maximum. Mean ± SD leukocytes was 5.50 + 2.95. The shortest length of stay was 3 days and the longest was 11 days. Mean ± SD length of stay was 5.21 ± 1.90 days. The result of multiple linear regression analysis showed a statistically non-significant relationship (p> 0.05) between age, sex, platelets, hematocrit, leukocytes, and length of stay. Conclusion:There is non-significant relationship between age, sex, platelet count, hematocrit value, leukocyte count, and length of stay.