Aim: To investigate the early events of bone regeneration of Ca(OH) 2 by studying biochemistry level of alkaline phosphatase (ALP) as guide for bone regeneration. Materials and Methods: The mandible of eight dogs was prepared by hole of 0.5×0.5 cm in depth and diameter in the apical to the molar teeth. This hole packed with Ca(OH) 2 powder mixed with distilled water to become as a paste. Samples of blood were collected pre-operatively considered as control groups [measuring level of serum ALP in experimental animals before implanted Ca(OH) 2 ], then at the 7, 10 and 15 day postoperatively considered as treated groups [measuring alteration of level of serum ALP in experimental animals after implanted Ca(OH) 2 ] for biochemical analysis of the level of serum ALP. Results: There was a significant difference at the day 10 following the operation between the control groups and the treated groups, while there was no significant difference at the day 7,and day 15 postoperatively between the control and the treated groups. Also the results showed that there was a high significant difference between the different postoperative days. Conclusion: The (CaOH) 2 powder mixed with distilled water have the ability to accelerate bone regeneration when it is placed in bone defect comparing to that defect filled with nothing.

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This study focused on the clinical evaluation of naproxen and ibuprofen efficacy on pain, swelling and trismus after surgical removal of impacted mandibular third molar, whether they used only pre-operatively or pre-and post-operatively. The number of patients included in the present study was 40, divided into four groups: Each group is 10 patients, the first group received naproxen as sodium 1hour pre-operatively followed by three times daily for five days post-operatively. Whereas the second group received naproxen as sodium three times daily for five days begins 1hour post-operatively. However, the third group had been given ibuprofen 1hour pre-operatively followed by three times daily for five days postoperatively. The fourth group administered ibuprofen three times daily for five days begins 1hour post-operatively.The pain was evaluated by the number of paracetamol tablets taken by the patients recorded on the pocket chart, whereas the swelling was measured subjectively. The trismus was evaluated by measuring the maximum mouth opening between the incisal edges of the maxillary and mandi-bular central incisors using the graduated vernier.The results showed that the use of naproxen as sodium 1hour pre-operatively minimized the pain, swelling and trismus significantly compared to ibuprofen.

Aim: To evaluate the response of intraoral soft tissue by low level laser light, histologically and biochemically. Materials and methods: The study was performed on (20) healthy rats. A clean two sided mucoperiosteal flap was raised opposite to the area of lower incisors. The rats were divided into two groups, ten for each. Histological specimens were taken at days 5 th ,9 th and 11 th postoperative period .The dose of laser therapy in each session was 0.75 J/cm 2. Each rat in each group received this dose daily for 11 th days at an interval of 15 minutes. Histopathological analysis were made for both groups detecting number of blood vessels (neovascularization),collagen arrangements and number of fibroblasts. Biochemical analysis of C-reactive protein(CRP) was also conducted. Results: Laser therapy showed enhancement of neovasculazation at days 5and 9 postoperatively .While collagen arrangement showed significant changes at the 5 th ,9 th and 11 th postoperative days. Biochemical analysis showed significant increase of CRP at the 5 th postoperative day. This increase was followed by a significant decrease at the 7 th postoperative day in comparison with the control group. Conclusion: The present results indicated that low level laser therapy at a dose of 0.75 J/cm 2 enhanced wound healing .

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