Over 80 taxa of mostly agriculturally important legumes were surveyed as sources of the metabolites, genistein and daidzein. Remarkably high concentrations (over 2 g • kg"^ dry weight) of the anticancer metabolite, genistein, were found in the leaves of Psoralea corylifolia (Indian bread root). All other legumes, with the exception of fermented soybean miso, had genistein levels <400 mg • kg"^ dry weight. Concentrations of over 1 g • kg~^ dry weight and 0.95 g • kg"^ dry weight of the anticancer metabolite, daidzein, were found in the stems of the fava bean {Vicia faba) and roots of kudzu vine {Pueraria lobata)^ respectively. From this survey, our results indicate that the legumes, lupine (Lupinus spp.), fava bean, {Vicia faha), soybeans {Glycine max), kudzu {Pueraria lobata), and psoralea {Psoralea corylifolia), are excellent food sources for both genistein and daidzein. Miso, a fermented soybean product, is also a rich source of both isoflavones.

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Cyclic enamides 1 of a type useful in the synthesis of naturally occurring chlorins, isobacteriochlorins, and corrins have been prepared by a process involving 5-exo-dig cyclization of the appropriate acetylenic amides 11. The desired cyclization is catalyzed by either n-Bu4NF or LiAl(NHBn)4.

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