This study came with the aim of identifying the impact of the green supply chain on sustainability. This research targeted managers at the senior and middle levels of the Pharmaceutical Industry in Jordan, as they were formulating the company's strategies and determining its policies. A purposive sample consisting of 258 managers was selected. To gather the data needed for the analysis, a self-report questionnaire was used formulated electronically through Google Forms. AMOS software was used to examine the research hypotheses. The study concluded that there was an impact of the green supply chain with its dimensions (Eco-Design, Green Distribution, Green Purchasing, Green Manufacturing, and Green Reverse Logistics) on sustainability. Based on this result, the researcher recommends pharmaceutical companies in Jordan to take green initiatives and the trends towards implementing a green supply chain approach that reduces the consumption of non-renewable resources and waste, and to establish special laws and regulations in the company that oblige employees to apply the green approach in their practices within the work.