Background: Cleft palate is a craniofacial disorder with definitive therapy using the V–Y pushback technique palatoplasty, which has the impact of leaving the bone exposed on the palate with long wound healing and a high risk of infection. Forest honey has high antioxidants and the ability to accelerate wound healing. Purpose: This study aims to determine the effect of forest honey on vascular endothelial growth factor (VEGF) expression to accelerate the wound healing process after palatoplasty biopsy. Methods: Posttest only control group design using Sprague Dawley palatoplasty was performed on 15 rats which were divided into three groups, namely the honey treatment (KP), Aloclair as a positive control (KPP), and aquadest as a negative control (KKN). As much as 25 mg of honey was given therapeutically, and VEGF expression analysis post-biopsy palatoplasty was measured using the ELISA test. ANOVA analysis was carried out to determine the significant differences between each treatment, and in silico analysis was conducted to determine the compounds’ role in honey on the mechanism of VEGF expression. Results: Statistical analysis of VEGF expression in the KP group was 41.10 ng/ml ± 0.26, the KKP was 39.57 ± 0.27, while the KKN was 33.26 ± 0.62 (p≤ 0.01). In silico study, genistein (C15H10O5) targets several signaling pathways such as PI3K-Akt, AMPK, and mTOR, affecting accelerated proliferation and angiogenesis. Conclusion: In wound healing acceleration, forest honey induced VEGF expression through the genistein mechanism of angiogenesis and cell proliferation.

- Oral and dental health is a condition that needs to be considered and maintained to improve the quality of life. One of the efforts made to maintain dental and oral health in the school environment is by conducting UKGS (Usaha Kesehatan Gigi Sekolah). In UKGS activities, teachers have a role in providing emergency treatment to relieve pain. The emergency treatment administered by teachers in schools can perform in cases such as avulsions, choking, and abscesses. This community service aims to increase the role of elementary school teachers through UKGS to maintain, improve the oral health of all students at SDN in the Karangtengah area, Baturaden District, Purwokerto. The method of implementation was basely on optimizing the potential of UKGS teacher cadres, including identification of target schools and participants, pre-test implementation, maturation, coaching, enhancement of UKGS teacher cadres. Coaching and training have been carried out for UKGS supervisors for abscess, choking and avelse conditions. Post-test activities to gain insight into emergency medicine and relieve tooth and mouth pain. Results: p data analysis using the Wilcoxon asymp test.sig.(2-tailed) of 0.001 (<0.05), this value indicates that there is an influence on the level of knowledge about emergency medicine. The analysis performed with the Wilcoxon Test; there was a significant difference (sig = 0.001, p <0.05). There was an increase in the average pre-test value of 76.92 and post-test of 97.85.Conclusion: There is increasing knowledge about emergency medicine to relieve tooth and mouth pain in elementary school teachers.

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Petechiae are round red lesions with a diameter of less than 2 mm located in the subcutaneous tissue or submucosa. Locations that often occur are the buccal mucosa, cheeks, lips, lateral tongue, base of the tongue, palate, oropharynx. The etiologic factors of petechiae consist of two types, local factors and systemic factors. Local factors that cause petechiae such as trauma, injury, fellatio, iatrogenic trauma. Systemic factors that cause petechiae such as platelet abnormalities, blood clotting factor disorders, blood vessel damage. An 8-year-old woman with her parents came to RSGMP Unsoed with complaints of red spots on the floor of the mouth, the patient was not aware of the redness under the tongue before treatment on the right lower tooth, did not feel pain and did not feel disturbed by this condition, The patient stated that this had never happened before. The patient is undergoing dental pulpotomy. Petechiae caused by trauma can heal by eliminating the etiologic factor.

Background: Heat-cured acrylic resin is one of the most widely used denture base materials. However, the residual monomer can reduce its mechanical properties, which affect physical properties such as surface roughness, resulting in high porosity—the results in the growth of fungal colonies. One way to improve these properties is to add a reinforcement material such as nano-hydroxyapatite (HAp) from the Anadara granosa shell. Nano-hydroxyapatite has a large surface area to act as a filler because of its strong bonding capacity and a smoother surface, and a higher density to improve mechanical properties. Purpose: This study aims to determine HAp powder's effect from the Anadara granosa shells on the surface roughness of heat-cured acrylic resin. Methods: This type of research used an experimental laboratory, research design posttest-only control group design. Twenty-four samples were used and divided into three groups: the acrylic resin group with 1%, 3% blood cockles shell HAp, and acrylic resin without HAp with simple random sampling. Results: The results showed that the lowest mean value of surface roughness was in a group with the addition of 3% HAp, at 1.696 ± 0.25058 µm. One-Way ANOVA test on roughness showed a significant difference between groups with p = 0.000 (p <0.05). Conclusion: This study concludes that there is an effect of HAp on the roughness of heat-cured acrylic resin.