We examined COVID-19 symptoms and infection rates, disruptions to functioning, and moderators of pandemic response for 620 youth with ADHD and 614 individually matched controls (70% male; Mage = 12.4) participating in the Adolescent Brain and Cognitive Development study. There were no group differences in COVID-19 infection rate; however, youth with ADHD were more likely to exhibit COVID-19 symptoms ( d = 0.25), greater sleep problems ( d = −0.52), fear and negative emotions to infection risk ( d = −0.56), trouble with remote learning ( d = −0.54), rule-breaking behavior related to COVID-19 restrictions ( d = −0.23), family conflict ( d = −0.13), and were less prepared for the next school year ( d = 0.38). Youth with ADHD were less responsive to protective environmental variables (e.g., parental monitoring, school engagement) during the pandemic and may need more specialized support with return to in-person schooling and daily activities.

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