Sturgeons are one of the most popular and valuable marketable fish species in the world in terms of their caviar and meat. The sturgeon species owing to indiscriminate fishing, water pollution, destroy of spawning places, and construction of dams, are listed as endangered fish by International Union for Conservation of Nature (IUCN, 2018). Today, sturgeon farming has been expanded rapidly in the world. Among the aquaculture of sturgeons, great sturgeon, Huso huso, has made a promising candidate because of high growth, resistance to stress factors and reception of formulated diets (Matani Bour et al.,

Nowadays, sturgeon aquaculture is a rapidly growing industry in the world, and considerable attention has been paid to this practice in Iran (Kalbassi et al., 2013). The great sturgeon, Huso huso, is one of the valuable species owning to their meat and especially caviar, and hence, nutritional administration of sturgeon is necessary for aquaculture. Fish meal (FM) is the most important component of the diet in carnivore fish mainly owing to its high protein value, essential n-3 fatty acids, indispensable amino acids, unknown growth factors, palatable taste, as well as contain the number of minerals, nucleotides and vitamins (Gatlin et al., 2007;Hardy, 2010;Yang et al., 2020). FM production has diminished while the demand surpasses supply resulting in a considerable shortage of sources and escalating prices (Ding et al., 2015;Hardy, 2010). This bottleneck has convinced researchers to investigate various alternatives to diminish their reliance on FM as a protein source over the past couple of decades.