Due to the characteristics of optical rotation, selective emission of polarized light, and circular dichroism, circularly polarized luminescent materials have aroused extensive attentions, and they have exhibited wide optoelectronic applications, such as optical data storage, liquid crystal display, and backlights in 3D displays. Here, the research progress of circularly polarized luminescent materials for organic optoelectronic devices is summarized. First, the definition and measurement of the circularly polarized light, such as optical rotatory dispersion, circular dichroism, and circularly polarized luminescence, are systematically introduced. Subsequently, the design strategies for various kinds of circularly polarized luminescent materials, including luminescent lanthanide and transition‐metal complexes, small organic luminophores, conjugated polymers, supramolecules, and liquid crystals are summarized. These materials exhibit circularly polarized luminescence with different magnitudes of luminescence dissymmetry values (glum). They are further applied in optoelectronic devices with excellent performance, and the influence factors on the glum values of these materials are presented in detail. Finally, the current opportunities and challenges in this rapidly growing research field are discussed systematically. The circularly polarized luminescent materials with large glum and high luminescence efficiency are very promising for applications in organic optoelectronic fields.

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Widely used engineered nanomaterials (NMs) display unique properties that may have impact on human health, and thus require a reliable evaluation of their potential cytotoxicity. There is a continuing need for real-time imaging techniques capable of studying the interactions between NMs and living alveolar epithelial cells under physiological conditions. A new developed noninvasive HPICM is designed for continuous high-resolution topographic imaging of living cells, which makes it an ideal tool to study NMs cytotoxicity in living alveolar epithelia by performing reliable repetitive scanning. In this review, we concisely introduced the operation principle of HPICM and its applications to real-time investigation of engineered NMs cytotoxicity in living alveolar epithelia. Published results demonstrate that non-contact HPICM combined with patch-clamp has the potential to become a powerful microscopy for real-time studies of NM-cell interactions under physiological conditions.

Continuous high-resolution observations of cell membrane would greatly aid the elucidation of the relationship between structure and function and facilitate the study of physiological processing in cell biology. However, high-resolution studying living neuron membrane structures and its functions is still a challenge in current nanobiology. The new developed Hoping Probe Ion Conductance Microscopy (HPICM) is designed for non-contact continuous high-resolution topographic imaging of living cells under physiological conditions. In this review, we concisely introduced the basic operation principle of HPICM and its applications in high spatial resolution imaging of two living neuron cell models, N-type SK-N-SH cells and NGF-differentiated sympathetic neuron-like PC12 cells. Combining HPICM with patch-clamp technique, we further investigated the functional ion-channel of under-differentiated neuron-like PC12 cells and demonstrated that NGF treatment promoted the outgrowth of neurites and increased the activity of TTX-sensitive sodium channel. All these results demonstrate that HPICM combined with patch-clamp technique offers high-resolution topographic imaging of living neurons with non-contact — making HPICM an ideal high-resolution imaging technique not to interact/interfere with living neurons during image acquisition, and provides detailed information about the relationship between membrane structures and ion-channel functions of living neurons at the same time, which has the potential to become a powerful microscopy for in-depth researching in neural nanobiology.